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UnknownEvaluation of the Potential Effect of Postbiotics Obtained from Honey Bees against Varroa destructor and Their Combination with Other Organic Products.
The Varroa destructor mite infests Apis mellifera colonies and causes significant harm. Traditional treatments have become less effective because of mite resistance development and can also generate residues inside beehives. This study aimed to gauge the efficacy of a beehive-derived p...
S-EPMC10816111 | biostudies-literature
UnknownSafe Care and Medication Intake Provided by Caregivers at Home: Reality Care Study Protocol.

Justification

Providing care to patients with several conditions and simultaneously taking several medications at home is inexorably growing in developed countries. This trend increases the chances of home caregivers experiencing diverse errors related with medication or care.

Objective

S-EPMC10419200 | biostudies-literature
UnknownGenomic characterization of MRSA recovered from people with cystic fibrosis during two Spanish multicentre studies (2013 and 2021).

Background

Chronic bronchopulmonary infection due to MRSA in people with cystic fibrosis (pwCF) has been associated with accelerated decline in lung function, increased hospitalizations and increased mortality.

Material and methods

We studied microbiological and genomic characteristic...
S-EPMC11487781 | biostudies-literature
ProteomicsHormone-dependent secretome profiling of bovine oviductal epithelial organoids
This project characterizes the hormone-dependent secretome of bovine oviductal epithelial organoids. Organoids were stimulated with estradiol or progesterone to mimic follicular and luteal phases, and their secretions were analyzed by LC-MS/MS. The resulting proteomic profiles closely matched native...
ORGANISM(S): Bos taurus (Bovine) 
2026-06-01 | PXD071140 | Pride
Oviductal fluid Secretion Bovine Organoids Oviduct Cow Epithelial cells 
ProteomicsBAP1 dysregulation impairs trophoblast differentiation and contributes to placental dysfunction in preeclampsia
This dataset profiles the proteomic effects of altering BAP1 expression in human trophoblast stem cells and trophoblast organoids. Samples from control, BAP1-overexpressing, and BAP1-knockdown conditions were analyzed by LC–MS/MS. DIA-NN–based quantification and differential analysis revealed BAP1-d...
ORGANISM(S): Homo sapiens (Human) 
2026-03-24 | PXD071497 | Pride
Organoids Trophoblast Bap1 Early-onset preeclampsia Placenta 
UnknownDose and administration time of indocyanine green in near-infrared fluorescence cholangiography during laparoscopic cholecystectomy (DOTIG): study protocol for a randomised clinical trial.

Background

One of the most severe complications in laparoscopic cholecystectomy (LC) is intraoperative bile duct injury (BDI). Despite its low incidence, the medical implications for the patient can be serious. Besides, BDI can also generate significant legal issues in healthcare. Different ...
S-EPMC9990661 | biostudies-literature
UnknownA GPU-accelerated fuzzy method for real-time CT volume filtering.
During acquisition and reconstruction, medical images may become noisy and lose diagnostic quality. In the case of CT scans, obtaining less noisy images results in a higher radiation dose being administered to the patient. Filtering techniques can be utilized to reduce radiation without losing diagn...
S-EPMC11694987 | biostudies-literature
UnknownSpecific Glutamylation Patterns of the Cytoskeleton Confer Neuroresistance to Lobe X of the Cerebellum in a Model of Childhood-Onset Neurodegeneration with Cerebellar Atrophy.
The cytoskeleton relies heavily on the dynamic nature of microtubules, regulated by post-translational modifications such as polyglutamylation and deglutamylation. Disruption of its internal balance, particularly through the absence of cytosolic carboxypeptidase 1 (CCP1), leads to cytoskeletal colla...
S-EPMC12610737 | biostudies-literature
UnknownTargeted genomic analysis of a predominant uncultured marine pelagiphage-host model via microfluidics and semipermeable capsule technology.
Microbes and their viruses drive central biogeochemical cycles on a global scale. Understanding the biology and ecology of virus-host interactions and their impact on ecosystems depends on our ability to develop tools that enable high-throughput screening of ecologically relevant, uncultured virus-h...
S-EPMC12404659 | biostudies-literature
UnknownSpanish Adaptation of Meaning-Centered Psychotherapy for Participants With Cancer: Study Protocol of a Randomized Control Trial.

Background

Meaning-Centered Psychotherapy (MCP) is effective in improving meaning in life, hope, optimism, self-efficacy, well-being, and quality of life, and in reducing stress in people with cancer. However, all the studies on the application of MCP in cancer patients have been carried out...
S-EPMC9301386 | biostudies-literature
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