Label-free quantitative affinity purification experiments were performed to identify the protein composition of pericentriolar satellites in the wild-type and two acentrosomal (stil KO; cep152 KO) DT40 cell lines.
SILAC quantitative affinity purification experiment was performed to compare the protein composition of pericentriolar satellites in the wild-type and acentrosomal (stil KO) DT40 cell lines.
Centrosomes are the principal microtubule-organizing centers of the cell, a cellular hub for protein degradation and play an essential role in mitotic spindle function that ultimately regulates chromosome segregation during mitosis. Centrosome maturation is achieved by strict control of protein acqu...
