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ProteomicsTissue Thermal Proteome Profiling
We introduce tissue Thermal Proteome Profiling (tissue-TPP) which enables the discovery of drug targets and off-targets as well as measurements of target occupancy in tissue samples derived from dosed animals. Here we report the first proteome-wide thermal stability map of tissues and organ-specific...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2020-01-07 | PXD016277 | Pride
Human Rat Tpp 
ProteomicsTissue Thermal Proteome Profiling
We introduce tissue Thermal Proteome Profiling (tissue-TPP) which enables the discovery of drug targets and off-targets as well as measurements of target occupancy in tissue samples derived from dosed animals. Here we report the first proteome-wide thermal stability map of tissues and organ-specific...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-01-07 | PXD015427 | Pride
Tpp Tissues Rat Cell line 
ProteomicsTissue Thermal Proteome Profiling
We introduce tissue Thermal Proteome Profiling (tissue-TPP) which enables the discovery of drug targets and off-targets as well as measurements of target occupancy in tissue samples derived from dosed animals. Here we report the first proteome-wide thermal stability map of tissues and organ-specific...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-07 | PXD015458 | Pride
Tpp Mouse Liver 
ProteomicsTissue Thermal Proteome Profiling
We introduce tissue Thermal Proteome Profiling (tissue-TPP) which enables the discovery of drug targets and off-targets as well as measurements of target occupancy in tissue samples derived from dosed animals. Here we report the first proteome-wide thermal stability map of tissues and organ-specific...
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD015373 | Pride
Tpp Human Blood 
ProteomicsTissue Thermal Proteome Profiling
We introduce tissue Thermal Proteome Profiling (tissue-TPP) which enables the discovery of drug targets and off-targets as well as measurements of target occupancy in tissue samples derived from dosed animals. Here we report the first proteome-wide thermal stability map of tissues and organ-specific...
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD015397 | Pride
Tpp Human Hl60 Hepg2 Thp1 
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