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MetabolomicsUntargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases. A more accurate risk stratification remains a key point in the study of NB and the availability of...
2023-07-14 | MTBLS4294 | MetaboLights
ProteomicsNET induced by different stimuli: a comparative proteomic analysis
Neutrophil extracellular traps (NET) formation is part of the neutrophil response to infections, but excessive or inappropriate NETosis may trigger the production of autoantibodies and cause organ damage in autoimmune disorders. Spontaneously netting neutrophils are not frequent and induction of NET...
ORGANISM(S): Homo sapiens (Human) 
2019-07-15 | PXD012951 | Pride
Neutrophil extracellular traps  proteomics  post-translational modifications 
UnknownscPanel: a tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets.
Not available
S-EPMC11442147 | biostudies-literature
UnknownA Comprehensive Proteomics Analysis of Urinary Extracellular Vesicles Identifies a Specific Kinase Protein Profile as a Novel Hallmark of Medullary Sponge Kidney Disease.
Not available
S-EPMC9171619 | biostudies-literature
ProteomicsPROTEOMIC SIGNATURES OF MONOCYTES IN HEREDITARY RECURRENT FEVERS
Hereditary recurrent fevers (HRF) are a group of monogenic autoinflammatory diseases characterized by auto-resolving attacks of sterile inflammation caused by mutations of MEFV, TNFRSF1A and MVK genes1-3. Familial Mediterranean fever (FMF) is the prototype of a HPR and is caused by gain-of-function ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD024068 | Pride
Mkd Traps Fmf 
ProteomicsProteomics of aqueous humor for biomarkers discovery in retinoblastoma
Background: Recent therapeutic advances have greatly improved the eye preservation rate in patients affected by retinoblastoma (RB), however local tumor control remains more difficult in the presence of resistant and/or relapsing retinal or vitreous disease. Thus, the identification of new biomarker...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD022218 | Pride
Proteomic analysis Retinoblastoma Humor aqueous Biomarkers 
ProteomicsProteomics of aqueous humor for biomarkers discovery in retinoblastoma (pt2)
Background: Recent therapeutic advances have greatly improved the eye preservation rate in patients affected by retinoblastoma (RB), however local tumor control remains more difficult in the presence of resistant and/or relapsing retinal or vitreous disease. Thus, the identification of new biomarker...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD022256 | Pride
Proteomic analysis Retinoblastoma Humor aqueous Biomarkers 
ProteomicsHUMAN PLASMAS FROM ELDERLY PEOPLE DISPLAY A PROTEIN SIGNATURE SUGGESTIVE OF A CHRONIC INFLAMMATORY STATE
Blood from elderly individuals exhibits a reduced "rejuvenating" effect compared to that of young donors, and plasma from older subjects used as a supplement in cell culture media is less effective than plasma from younger individuals. A mass spectrometry-based proteomic analysis of plasma samples f...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD063248 | Pride
Ms spectrometry (ms) Aging Inflammaging Plasma proteome Immune senescence 
UnknownSphingomyelin and Medullary Sponge Kidney Disease: A Biological Link Identified by Omics Approach.
Not available
S-EPMC8187918 | biostudies-literature
ProteomicsCytokine-induced GBP1 release from human ovarian cancer cells
Background: In previous studies we showed that IL-27 shares several effects with IFN-γ in human cancer cells. To identify novel extracellular mediators, potentially involved in epithelial ovarian cancer (EOC) biology, we analyzed the effect of IL-27 or IFN-γ on the secretome of EOC cells in culture....
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016479 | Pride
Guanosyl binding protein 1 Interleukin-27 Microenvironment. Interferon- Secretome Ovarian cancer 
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