Sort   by:  
 Page size 
MetabolomicsGenetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway (Part 1)
Not available
ORGANISM(S): Plasmodium falciparum 
ST002106 | MetabolomicsWorkbench
ProteomicsSecretome analysis of ferroptotic Pfa1 cells
Pfa1 cells undergo ferroptosis upon induction of knockout of the glutathione peroxidase 4 via tamoxifen treatment. Ferroptosis is a recently discovered, iron-dependent mode of cell death, whose potency to evoke an immune response in the surrounding tissue remains to be clarified. The goal of this pr...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-24 | PXD050979 | Pride
Mass spectrometry Cell culture Immune response Ferroptosis Secretome 
ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during erastin-induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. In the first part of this ba...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-11 | PXD041463 | Pride
Proteomics Ferroptosis Mouse embryonic fibroblasts Erastin Glutathione peroxidase 4 Liproxtatin-1 Pfa1 Cell death 
ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during ML210-induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. We used ML210 (SML0521, Sigma...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-10 | PXD041327 | Pride
Proteomics Mouse embryonic fibroblasts Ferroptosis Ml210 Erastin Glutathione peroxidase 4 Pfa1 Cell death 
UnknownRegulation of the DEAH/RHA helicase Prp43 by the G-patch factor Pfa1.
Not available
S-EPMC9860317 | biostudies-literature
ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during L-Buthionine-sulfoximine (BSO) induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. We used L-Buthionine-sulfoxim...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-12 | PXD041415 | Pride
Bso Proteomics Mouse embryonic fibroblasts Ferroptosis Erastin Glutathione peroxidase 4 L-buthionine-sulfoximine Pfa1 Cell death 
UnknownThe G-patch activators Pfa1 and PINX1 exhibit different modes of interaction with the Prp43 RNA helicase.
Not available
S-EPMC7971346 | biostudies-literature
UnknownLoss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth.
Not available
S-EPMC12309711 | biostudies-literature
GenomicsLoss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth [RNA-seq]
Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth [RNA-seq]
PRJNA1148399 | ENA
GenomicsLoss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth [CUT&RUN]
Loss of LDOC1 by chromatin compaction in mesenchymal tumor cells is required for PFA1 ependymoma growth [CUT&RUN]
PRJNA1148394 | ENA
Sort   by:  
 Page size