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ProteomicsProteomic shift in mouse embryonic fibroblasts Pfa1 during L-Buthionine-sulfoximine (BSO) induced ferroptosis
This report provides data on ferroptosis induced proteomic response in immortalized mouse embryonic fibroblasts which are 4-OH-TAM-inducible Gpx4−/− (referred to as Pfa1 cells). Pfa1 cells are a valuable, widespread and well characterized model for ferroptosis research. We used L-Buthionine-sulfoxim...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-12 | PXD041415 | Pride
Bso Proteomics Mouse embryonic fibroblasts Ferroptosis Erastin Glutathione peroxidase 4 L-buthionine-sulfoximine Pfa1 Cell death 
Unknownl-Buthionine Sulfoximine Detection and Quantification in Polyurea Dendrimer Nanoformulations.
Not available
S-EPMC6749587 | biostudies-literature
UnknownAdenosine Improves Mitochondrial Function and Biogenesis in Friedreich's Ataxia Fibroblasts Following L-Buthionine Sulfoximine-Induced Oxidative Stress.
Not available
S-EPMC10136261 | biostudies-literature
TranscriptomicsBSO-treated blastocysts vs CTL-treated blastocysts
In order to understand how in vitro culture affects embryonic quality, we analyzed survival and global gene expression in bovine blastocysts after exposure to increased oxidative stress conditions of IVC. A pro-oxidant agents that act intra-cellularly by inhibiting GSH synthesis (0.4 mM buthionine s...
ORGANISM(S): Bos taurus 
2012-11-14 | E-GEOD-42280 | biostudies-arrayexpress
ProteomicsFremont et al 2023 - Arsenic stress triggers active exudation of arsenic-phytochelatin complexes from Lupinus albus roots
Arsenic stress triggers active exudation of arsenic-phytochelatin complexes from Lupinus albus roots
ORGANISM(S): Lupinus Albus (ncbitaxon:3870) 
2023-10-10 | MSV000093078 | MassIVE
UnknownEnhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation.
Not available
S-EPMC4601049 | biostudies-literature
ProteomicsProteomic and cellular responses against mutagenesis
Endogenous stress represents a major source of genome instability, but is in essence difficult to apprehend. Incorporation of labeled radionuclides into DNA constitutes a tractable model to analyze cellular responses to endogenous attacks. Here we show that incorporation of [3H]thymidine into CHO ha...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2016-07-15 | PXD003542 | Pride
Endogenous stress Tritium Oxidative stress Proteomic Mutagenesis Low doses 
TranscriptomicsTranscription profiling of human U266, MM.1s, KMS11, 8226/S multiple myeloma cell lines treated with arsenic
We used microarrays to examine changes in gene expression in multiple myeloma cell lines following treatment with arsenic trioxide and darinaparsin Experiment Overall Design: Four multiple myeloma cell lines (U266, MM.1s, KMS11, 8226/S) were treated with either arsenic trioxide (ATO) for 6, 24, or 4...
ORGANISM(S): Homo sapiens 
2009-02-01 | E-GEOD-14519 | biostudies-arrayexpress
UnknownStructural basis for feedback and pharmacological inhibition of Saccharomyces cerevisiae glutamate cysteine ligase.
Not available
S-EPMC2863196 | biostudies-literature
UnknownMultichiral Half-Sandwich Ru(II) and Os(II) Anticancer Complexes Containing a Glutathione Synthesis Inhibitor.
Not available
S-EPMC12728982 | biostudies-literature
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