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Mitochondria are essential organelles involved in critical biological processes such as energy metabolism and cell survival. Their dysfunction is linked to numerous human pathologies that often manifest in a tissue-specific manner. Accordingly, mitochondria fitness depends on versatile proteomes spe...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-03 | PXD030062 | Pride
We used mass-spectrometry based phosphoproteomics and computational methods to identify patient-specific drug targets in primary CCA and CCA-derived cell lines. We analyzed 13 primary CCA with matched background tissue and 8 different cell lines leading to the identification and quantification of >1...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD027329 | Pride
Preeclampsia (PE) is a leading cause of maternal and fetal morbidity and mortality and is characterized by a wide spectrum of impaired maternal and fetal vascular function. Aryl hydrocarbon receptor (AhR, a ligand-activated transcription factor) plays a critical role in regulating vascular developme...
ORGANISM(S): Homo sapiens (Human) 
2025-02-10 | PXD047834 | Pride
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