Sort   by:  
 Page size 
ProteomicsMolecular mechanism of β-arrestin 2 interaction with phosphorylated intracellular loop 3 of dopamine receptor D2
G protein-coupled receptors (GPCRs) are essential signaling molecules involved in various physiological processes, with β-arrestins playing crucial roles in receptor desensitization, internalization, and G protein-independent signaling. Although the interaction between the phosphorylated C-terminal ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-02-09 | PXD056442 | Pride
Arrestin Dopamine receptor d2 Phosphorylated intracellular loop 3 Hydrogen/deuterium exchange mass spectrometry (hdx-ms) 
UnknownThe second intracellular loop of the yeast Trk1 potassium transporter is involved in regulation of activity, and interaction with 14-3-3 proteins.
Not available
S-EPMC10165143 | biostudies-literature
UnknownDifferential Role of Serines and Threonines in Intracellular Loop 3 and C-Terminal Tail of the Histamine H4 Receptor in β-Arrestin and G Protein-Coupled Receptor Kinase Interaction, Internalization, and Signaling.
Not available
S-EPMC7155198 | biostudies-literature
UnknownMolecular mechanism of β-arrestin 2 interaction with phosphorylated intracellular loop 3 of dopamine receptor D2
Not available
S-EPMC12334658 | biostudies-literature
UnknownThe presenilin loop region is essential for glycogen synthase kinase 3 β (GSK3β) mediated functions on motor proteins during axonal transport.
Not available
S-EPMC6097159 | biostudies-literature
ProteomicsGRK2/3-regulated, but not constitutive, phosphorylation of the G protein-coupled receptor GPR84 controls arrestin interactions and subsequent function
Although the GPR84 activators 2-HTP and 6-OAU promoted phosphorylation of human GPR84 and its interactions with arrestin-3, PSB-16671 and DL-175 did not. Replacement of all 21 serine and threonine residues within the third intracellular loop, but not the 2 serines in the C-terminal tail, eliminated ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD031252 | Pride
Gpcr Phosphorylation 
UnknownTubulin binds to the cytoplasmic loop of TRESK background K⁺ channel in vitro.
Not available
S-EPMC4022642 | biostudies-literature
UnknownState-dependent regulation of cystic fibrosis transmembrane conductance regulator (CFTR) gating by a high affinity Fe3+ bridge between the regulatory domain and cytoplasmic loop 3.
Not available
S-EPMC3003342 | biostudies-literature
UnknownLPA3 Receptor Phosphorylation Sites: Roles in Signaling and Internalization.
Not available
S-EPMC11122405 | biostudies-literature
TranscriptomicsSTATs Shape the Active Enhancer Landscape of T Cell Populations
Signaling pathways are intimately involved in cellular differentiation, allowing cells to respond to their environment by regulating gene expression. While enhancers are recognized as key elements that regulate selective gene expression, the interplay between signaling pathways and actively used enh...
ORGANISM(S): Mus musculus 
2012-11-24 | E-GEOD-40463 | biostudies-arrayexpress
Sort   by:  
 Page size