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ProteomicsATG9A TurboID - ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair
Lysosome damage activates multiple pathways to prevent lysosome-dependent cell death, including a repair mechanism involving ER-lysosome membrane contact sites, phosphatidylinositol 4-kinase-2a (PI4K2A), phosphatidylinositol-4 phosphate (PI4P) and oxysterol-binding protein-related proteins (ORPs) li...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD056417 | Pride
Arfip2 Membrane trafficking Autophagy Lysosomal damage Lysosome Ap-3 Pi4k2a Atg9a Pi4p 
ProteomicsGFP-Trap ARFIP2 - ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair
Lysosome damage activates multiple pathways to prevent lysosome-dependent cell death, including a repair mechanism involving ER-lysosome membrane contact sites, phosphatidylinositol 4-kinase-2a (PI4K2A), phosphatidylinositol-4 phosphate (PI4P) and oxysterol-binding protein-related proteins (ORPs) li...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD056398 | Pride
Arfip2 Membrane trafficking Autophagy Lysosomal damage Lysosome Ap-3 Pi4k2a Atg9a Pi4p 
UnknownGABARAPs regulate PI4P-dependent autophagosome:lysosome fusion.
Not available
S-EPMC4460452 | biostudies-literature
UnknownA heat-sensitive Osh protein controls PI4P polarity.
Not available
S-EPMC7071650 | biostudies-literature
UnknownReconstitution of ORP-mediated lipid exchange coupled to PI4P metabolism.
Not available
S-EPMC10927502 | biostudies-literature
UnknownDynamic assessment of PI4P metabolism using split GFP based sensors.
Not available
S-EPMC12370885 | biostudies-literature
UnknownSterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP.
Not available
S-EPMC5666618 | biostudies-literature
UnknownPI4P and BLOC-1 remodel endosomal membranes into tubules.
Not available
S-EPMC9524204 | biostudies-literature
UnknownPI4P-Containing Vesicles from Golgi Contribute to Mitochondrial Division by Coordinating with Polymerized Actin
Not available
S-EPMC10095118 | biostudies-literature
UnknownINTRACELLULAR TRANSPORT. PI4P/phosphatidylserine countertransport at ORP5- and ORP8-mediated ER-plasma membrane contacts.
Not available
S-EPMC4638224 | biostudies-literature
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