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Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Genome Biology, Science for Life Laboratory (1)
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NeuroEpigenetics Lab - Department of Cellular, Computational and Integrative Biology - CIBIO University of Trento, Via Sommarive 9, I - 38123 Povo (Trento) (1)
Professor of Molecular Neurogenetics CIMR Deputy Director Cambridge Institute of Medical Research (CIMR) University of Cambridge (1)
Proteas Bioanalytics, The Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA (1)
Proteomic and Mass Spectrometry Laboratory Institute for Animal Production Systems in Mediterranean Environments (ISPAAM) National Research Council ITALY (1)

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xref:EuropePMC:PMC7434839 (1)
xref:PubMed:32903390 (1)
xref:PubMed:41198411 (1)
xref:EuropePMC:PMC8556283 (1)

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Evidence of a DHA signature in the lipidome and metabolome of human hepatocytes

Cell supplementation with bioactive molecules often causes a perturbation in the whole intracellular environment. Omics techniques can be applied for the assessment of this perturbation. In this study, the overall effect of docosahexaenoic acid (DHA) supplementation on cultured human hepatocyte lipi...

2017-03-02 | MTBLS419 | MetaboLights

Condensin association with chromosomes depends on a DNA binding domain formed by its HEAT-repeat subunits

Condensin protein complexes play central roles in the three-dimensional organization of chromosomes during mitotic and meiotic cell divisions. How condensin interacts with its chromatin substrates to promote sister chromatid decatenation and segregation is largely unknown. Previous work suggested th...

ORGANISM(S): Saccharomyces cerevisiae

2014-05-16 | E-GEOD-55948 | biostudies-arrayexpress

LiP-Quant, an automated chemoproteomic approach to identify drug targets in complex proteomes, p2

Chemoproteomics is a key technology to characterize the mode of action of drugs, as it directly identifies the protein targets of bioactive compounds and aids in developing optimized leads. We have developed a drug target deconvolution approach with an automated data analysis pipeline, based on limi...

ORGANISM(S): Homo sapiens (Human)

2020-09-09 | PXD018204 | Pride