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Genomics
CDR3 sequencing of in vitro adult peripheral blood gammadelta T cell expansions
Quantitative proteomic studies are contributing greatly to our understanding of the spermatozoon through the provision of detailed information on the proteins spermatozoa acquire and shed in the acquisition of fertility. Extracellular vesicles (EVs) are thought to aid in the delivery of proteins to ...
ORGANISM(S): Ovis aries 
2020-05-08 | PXD017537 | Pride
While obesity has links to poor semen parameters and reduced fertility, the causative links between obesity and male infertility are unclear, particularly on a molecular level. We investigated how obesity impacts the human sperm proteome, to further understand any implications for fertility. Sperm p...
ORGANISM(S): Homo sapiens (Human) 
2020-02-18 | PXD014849 | Pride
Cryopreservation causes significant lethal and sub-lethal damage to spermatozoa. In order to improve freezing outcomes, a comprehensive understanding of sub-lethal damage is required. Cryopreservation induced changes to sperm proteins have been investigated in several species, but few have employed ...
ORGANISM(S): Ovis aries 
2018-04-26 | PXD009331 | Pride
While assisted reproductive technologies (ARTs) are widely used in domestic animals, successful implementation of ARTs to conserve wildlife species remains challenging. In macropods, crucial aspects of fundamental reproductive biology, including changes induced by epididymal maturation, remain unkno...
ORGANISM(S): Macropus giganteus 
2025-09-29 | PXD064577 | Pride
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