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ProteomicsPathogenicity of human PLA2R1-antibodies in minipigs: a pilot study
Description Primary membranous nephropathy (MN) is an autoimmune kidney disease histomorphologically defined by subepithelial deposition of immune complexes in the glomeruli, and exhibits a high risk for end-stage kidney disease. Circulating antibodies against phospholipase A2 receptor 1 (PLA2R1) a...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-12-21 | PXD039024 | Pride
Kidney Membranous nephropathy Pla2r1 Complement Pathogenecity Miniature swine Glomeruli 
UnknownPhospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy.
Not available
S-EPMC3609136 | biostudies-literature
UnknownPLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.
Not available
S-EPMC7887270 | biostudies-literature
UnknownPLA2R1 and HLA-DQA1 SNP in patients with primary membranous nephropathy.
Not available
S-EPMC12373238 | biostudies-literature
UnknownEctodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17.
Not available
S-EPMC11301074 | biostudies-literature
UnknownAnti-PLA2R1 Antibodies Containing Sera Induce In Vitro Cytotoxicity Mediated by Complement Activation.
Not available
S-EPMC7012209 | biostudies-literature
UnknownImmunological Pathogenesis of Membranous Nephropathy: Focus on PLA2R1 and Its Role.
Not available
S-EPMC6691064 | biostudies-literature
UnknownHLA-DQA1 and PLA2R1 polymorphisms and risk of idiopathic membranous nephropathy.
Not available
S-EPMC3913240 | biostudies-literature
UnknownPLA2R1 Inhibits Differentiated Thyroid Cancer Proliferation and Migration via the FN1-Mediated ITGB1/FAK Axis.
Not available
S-EPMC10216500 | biostudies-literature
UnknownOrganelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth.
Not available
S-EPMC10921702 | biostudies-literature
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