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UnknownPlant-made pharmaceuticals: exploring studies for the production of recombinant protein in plants and assessing challenges ahead.
Not available
S-EPMC9931573 | biostudies-literature
ProteomicsDifferential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases
The hydroxylation of proline residues to 4-trans-hydroxyproline (Hyp) is a common post-translational protein modification in plants, mediated by prolyl 4-hydroxylases (P4Hs). Hyps predominantly occur in a group of cell wall proteins, the Hydroxyproline-rich glycoproteins (HRGPs), where they are freq...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2024-08-10 | PXD051497 | Pride
O-glycosylation Posttranslational protein modification Erythropoietin Prolyl-hydroxylation Biopharmaceutical Plant-made pharmaceutical 
UnknownA Perspective on the Development of Plant-Made Vaccines in the Fight against Ebola Virus.
Not available
S-EPMC5344899 | biostudies-literature
UnknownInduction of a dwarf phenotype with IBH1 may enable increased production of plant-made pharmaceuticals in plant factory conditions.
Not available
S-EPMC11388859 | biostudies-literature
ProteomicsA microbial supply chain for production of anti-cancer drug vinblastine
Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential anti-cancer therapeutics vinblastine and vincristine. As MIAs are difficult to chemically synthesize, the world’s supply chain for vinblastine relie...
ORGANISM(S): Saccharomyces Cerevisiae 
2022-09-09 | PXD024976 | panorama
UnknownEvaluation of extracts from Sida acuta, Phyllanthus amarus, Parkia biglobosa and their herbal ointment for therapeutic and biological activities.
Not available
S-EPMC10481288 | biostudies-literature
OtherDereplication of Natural Bioactive Products from Leaves of Stryphnodendron pulcherrimum
Stryphnodendron pulcherrimum is a species known to have a high content of tannins. Accordingly, its preparations are used in southern Para, Brazil, for their anti-inflammatory and antimicrobial activities, but so far, its chemical profile composition remains essentially unknown. We herein describe t...
ORGANISM(S): Stryphnodendron Pulcherrimum (ncbitaxon:397652) 
2021-12-14 | MSV000088562 | MassIVE
TranscriptomicsPharmaceutical industry effluent diluted 1:500 affects gene expression, CYP1A activity and plasma phosphate in fish
Patancheru, near Hyderabad, India, is a major production site for the global bulk drug market. About 90 manufacturers send their wastewater to a common treatment plant in Patancheru. Extraordinary high levels of a wide range of pharmaceuticals have recently been demonstrated in the treated effluent....
ORGANISM(S): Oncorhynchus mykiss 
2010-06-24 | E-GEOD-15124 | biostudies-arrayexpress
UnknownEngineering Nicotiana benthamiana for production of active cannabinoid synthases via secretory pathway optimization.
Not available
S-EPMC11647631 | biostudies-literature
UnknownAn Ethnobotanical study of medicinal plants in Taskopru (Kastamonu-Turkey).
Not available
S-EPMC9630845 | biostudies-literature
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