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MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (Imaging MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS769 | MetaboLights
MetabolomicsIn plaque-mass spectrometry imaging of a bloom-forming alga during viral infection reveals a metabolic shift towards odd-chain fatty acid lipids (GC- and LC-MS assays)

Tapping into the metabolic cross-talk between a host and its virus can reveal unique strategies employed during infection. Viral infection is a dynamic process that generates an evolving metabolic landscape. Gaining a continuous view into the infection process is highly challenging and is limited...

2018-11-29 | MTBLS767 | MetaboLights
MetabolomicsDistinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status
Not available
ORGANISM(S): Homo sapiens 
ST000496 | MetabolomicsWorkbench
ProteomicsMolecular Landscape of Atherosclerotic Plaque Progression: Insights from Proteomics
This dataset comprises proteomic profiles of 87 human carotid atherosclerotic plaques from patients undergoing carotid endarterectomy (CEA). The study employed an integrated approach using Data Independent Acquisition (DIA) proteomics. A total of 87 human carotid plaques were analyzed to identify an...
ORGANISM(S): Homo Sapiens 
2025-03-26 | PXD062283 |
ProteomicsUnstable Atherosclerotic Plaque Proteome
The rupture of unstable atherosclerotic plaques, leading to debilitating or fatal thrombotic events, is a major health burden worldwide. Limited understanding as to the molecular drivers of plaque instability and rupture hinders efforts in diagnosis and treatment prior to thrombotic events. Utilisin...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD030857 | Pride
Atherosclerosis Therapeutic Mouse Plaque Proteome 
ProteomicsMulti-Omics’ Defines Unstable and Stable Atherosclerotic Plaque Signatures and Identifies Novel Targets for Plaque Stabilisation
The rupture of unstable atherosclerotic plaques, leading to debilitating or fatal thrombotic events, are a major health concern worldwide. Limited understanding as to the molecular drivers of plaque destabilisation and rupture hinders efforts in diagnosis and treatment prior to thrombotic events. Us...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-24 | PXD018224 | Pride
Atherosclerosis Mouse Plaque Thrombosis 
ProteomicsImpact of different oral treatments on the composition of the supragingival plaque microbiome
Using a metaproteome approach in addition to a standard plaque-regrowth study, this study examined the impact of different concentrations of lactoperoxidase (LPO) in two lozenge formulations on early plaque formation, microbiome composition, and active biological processes in young orally healthy vo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-29 | MSV000089755 | MassIVE
TranscriptomicsTranscriptome Analysis of Human Supragingival Dental Plaque Microbiome from 19 Twin Pairs with and without Dental Caries
The study aims to assess gene expression in plaque samples collected from twin pairs that are both concordant and discordant with respect to dental Caries diagnosis. File Naming Conventions are as follows: Patient ID : 4 digit identifier Diagnosis : Caries Negative(CN) or Caries Positive(CP)...
ORGANISM(S): human oral metagenome 
2011-09-26 | E-GEOD-31439 | biostudies-arrayexpress
TranscriptomicsMulti-platform approach for plaque-derived biomarkers for the vulnerable plaque. Challenges and promises.
Plaque rupture and subsequent thrombus formation is responsible for the majority of clinical complications of atherosclerosis and nonetheless our understanding of what underlies plaque vulnerability and rupture is still sparse and mostly deductively based on animal models and in vitro studies. We ad...
ORGANISM(S): Homo sapiens 
2014-05-17 | E-MTAB-2055 | biostudies-arrayexpress
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