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ProteomicsATG9A is a component of the ESCRT system and governs plasma membrane repair
ATG9 is often described as the sole transmembrane protein among the core autophagy factors. The mammalian ATG9A is notorious for trafficking through numerous cellular compartments including the plasma membrane. The reasons for ATG9As wide intracellular distribution and its role at the PM are not ful...
ORGANISM(S): Homo 
2019-10-30 | MSV000084519 | MassIVE
GenomicsPlasma Membrane Integrity Signaling
Plasma Membrane Integrity Signaling
PRJNA701242 | ENA
Proteomicsα-arrestin-dependent endocytosis after cycloheximide treatment
To identify new plasma membrane (PM) proteins that require α-arrestins for endocytosis, we performed an iTRAQ-based quantitative proteomic screening. We analysed and compared the PM proteome for each arrestin knockout (art∆) strain to a WT strain after a 90 min cycloheximide (CHX) treatment. CHX is ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-09-25 | PXD014695 | Pride
Endocytosis Arrestin Plasma membrane Cycloheximide 
ProteomicsProteomic analysis of plasma membrane and tonoplast from the leaves of a mangrove plant Avicennia officinalis
We used gel electrophoresis coupled with LC-MS based proteomics to identify key transport proteins in the plasma membrane (PM) and tonoplast fractions of Avicennia officinalis leaves. This was part of our attempts to understand salt tolerance and secretion in mangrove plant species. PM and tonoplast...
ORGANISM(S): Avicennia 
2014-11-18 | PXD000837 | Pride
Tonoplast Plasma membrane Proteomics Avicennia officinalis Salt secretion 
ProteomicsRabA2b overexpression alters the Plasma-Membrane Proteome and Improves Drought Tolerance in Arabidopsis
Rab proteins are small GTPases that are important in the regulation of vesicle trafficking. RabA2b was identified through data mining to be stress responsive. Little is known about the involvement of RabA in plant responses to abiotic stresses. Promoter analysis of RabA2b showed strong activity duri...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-02-15 | PXD028140 | Pride
Arabidopsis Plasma-membrane Drought 
ProteomicsCharacterization of Plasma Membrane Proteins in Stylosanthes Leaves and Roots Using Simplified Enrichment Method
Plant plasma membranes (PMs) play an important role in maintaining the stability of the intracellular environment and exchanging information with the external environment. Therefore, deciphering dynamics of PM proteome provides crucial information for elucidating cellular regulation in response to d...
ORGANISM(S): Stylosanthes guianensis 
2022-12-14 | PXD037423 | Pride
Proteomics Plasma membrane Brij-58 treatment Protein enrichment Stylosanthes 
ProteomicsThe endocytic TPLATE complex internalizes ubiquitinated plasma membrane cargo
Endocytosis controls the perception of stimuli by modulating protein abundance at the plasma membrane. In plants, clathrin-mediated endocytosis is the most prominent internalization pathway and relies on two multimeric adaptor complexes, the AP-2 and the TPLATE complex (TPC). Ubiquitination is a wel...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-03-11 | PXD035444 | Pride
Ap-ms Arabidopsis Tplate complex Endocytosis 
ProteomicsPlasma membrane proteomics
Aluminum (Al) toxicity in acid soil is a worldwide agricultural problem that inhibits crop growth and productivity. However, the signal pathways associated with Al tolerance in plants still remain largely unclear. In this study, tandem mass tag (TMT)-based quantitative proteomic methods was used to ...
ORGANISM(S): Glycine max 
2020-06-25 | PXD017160 | Pride
Aluminum resistance Plasma membrane Tmt Prm Tbs Proteomics 
ProteomicsVAP-mediated membrane tethering mechanisms implicate ER-PM contact function in pH homeostasis
MS analyses of interactome of full-length (i.e., Scs2 and Scs22) and TM-truncated (i.e., Scs2N and Scs22N) fission yeast VAPs.
ORGANISM(S): Schizosaccharomyces Pombe (fission Yeast) 
2024-08-09 | PXD053887 | JPOST Repository
ModelsKoenig2012 - Hepatic Glucose Metabolism
Kinetic Modeling of Human Hepatic Glucose Metabolism in Type 2 Diabetes Mellitus Predicts Higher Risk of Hypoglycemic Events in Rigorous Insulin Therapy* Kinetic Model of Human Hepatic Glucose Metabolism in T2DM Authors ...
2005-01-01 | MODEL1209260000 | BioModels
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