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TranscriptomicsSpheres culture from lung adenocarcinoma pleural effusions
Briefly, we analyzed gene expression profiles in adherent cultures compared to sphere cultures from malignant pleural effusions (MPEs). MPEs could represent an opportunity to culture a wide variety of cancer cells from different donors. In this study, we set up culture conditions for cancer cells de...
ORGANISM(S): Homo sapiens 
2011-12-02 | E-MEXP-3025 | biostudies-arrayexpress
ProteomicsQuantitative proteomics revealed novel protein biomarkers to distinguish malignant pleural effusion from benign pleural effusion
A four-dimensional independent data acquisition (4D-DIA) proteomic was performed to determine the differentially expressed proteins in pleural effusion samples collected from ung adenocarcinoma MPE, BPE (tuberculosis pleural effusion (TPE) and parapneumonic effusion (PPE)).
ORGANISM(S): Proteinus 
2024-03-08 | PXD050477 |
ProteomicsUnbiased undepleted malignant pleural effusion proteomics study
Pleural effusion (PE) occurs as a consequence of various pathologies. Malignant effusion due to lung cancer is one of the most frequent causes. Methods for accurate differentiation of malignant from benign PE cases are an unmet clinical need. Proteomics profiling of PE has shown promising results. H...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035884 | Pride
Pleural effusion Real life clinical cohort Human Biomarker Malignant 
TranscriptomicsLiquid Biopsy-Based Single-Cell Transcriptome Profiling Characterizes Heterogeneity of Disseminated Tumor Cells from Lung Adenocarcinoma
To decipher the heterogeneity and distinct molecular signatures of disseminated tumor cells, we profiled the transcriptomes single cells from malignant pleural effusion. RNA-seq was done using the standard 10x chromium v3 chemistry.
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8530 | biostudies-arrayexpress
GenomicsMetagenome of pleural effusion
Metagenome of pleural effusion
PRJNA906763 | ENA
ProteomicsHuman pleural effusion LC-MSMS
We screened pleural effusion proteomes of mesothelioma and lung adenocarcinoma patients to identify novel soluble mesothelioma biomarkers. We performed quantitative mass spectrometry-(MS-) based proteomics using isobaric tags for relative and absolute quantification (iTRAQ) and used narrow range imm...
ORGANISM(S): Homo sapiens (Human) 
2014-01-14 | PXD000531 | Pride
Human Ief Pleural effusions Malignant mesothelioma Hirief Msms Lung cancer Itraq Ipg 
ProteomicsMapping the soluble human leukocyte antigen peptidome of pleural effusions reveals lung and tumor-associated antigens
Soluble HLA (sHLA) molecules released to the plasma, carry their original peptide cargo and provide insight into the protein synthesis and degradation schemes of their source cells and tissues. Other body fluids, such as pleural effusions, may also contain sHLA-peptide complexes, and can potentially...
ORGANISM(S): Homo sapiens (Human) 
2022-05-25 | PXD027766 | Pride
Tumor antigens Immunopeptisome Pleural effusion Cancer/testis antigens Hla peptidome Lung cancer Lc-ms/ms 
GenomicsEfferocytosis fuels malignant pleural effusion through TIMP1
Efferocytosis fuels malignant pleural effusion through TIMP1
PRJNA723335 | ENA
GenomicsExpression of miRNA in exosomes from transudative pleural effusion and tuberculous pleural effusions
Expression of miRNA in exosomes from transudative pleural effusion and tuberculous pleural effusions
PRJNA722251 | ENA
GenomicsMicroarray expression profiles of circular RNA in malignant pleural effusion
Microarray expression profiles of circular RNA in malignant pleural effusion
PRJNA505174 | ENA
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