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Polydopamine (PDA) is a polymer obtained from the self-polymerization of dopamine monomers; during the synthesis process, spherical nanoparticles are formed (PDA NPs), presenting several interesting properties such as high drug encapsulation capacity, easy and versatile surface modification, ability...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051299 | Pride
Reactive oxygen species (ROS) are active molecules involved in several biological functions. When the production of ROS is not counterbalanced by the action of protective antioxidant mechanisms present in living organisms, a condition of oxidative stress can arise with consequent damage to biologica...
ORGANISM(S): Homo sapiens (Human) 
2022-06-22 | PXD032916 | Pride
Controlled Nutrient Delivery to Pancreatic Islets Using Polydopamine-Coated Mesoporous Silica Nanoparticles
The precise control of cell activity is crucial for understanding and potentially treating many disorders. Focusing on neurons and myotubes, recent advancements in nanotechnology have introduced photoresponsive nanoparticles as a novel tool for modulating cell function with high spatial and temporal...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-04-23 | PXD061533 | Pride
Non-alcoholic fatty liver disease (NAFLD), or hepatic steatosis, has become one of the most common pathologies among liver-related disorders. The rapid accumulation of fat in this organ, and the consequent increment in oxidative stress levels, have been recognized as one of the main factors involved...
ORGANISM(S): Homo sapiens (Human) 
2024-10-02 | PXD046524 | Pride
In the present study, we designed a nanoscale platform for the sustained and controlled delivery of nutrients to pancreatic islets-upon transplantation. Our platform consists of a mesoporous silica nanoparticle (MSNP), loaded with glutamine (G), an essential amino acid required for islet survival an...
ORGANISM(S): Mus musculus 
2023-12-04 | GSE247020 | GEO
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