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Anomalous posterior vitreous detachment (aPVD) is involved in the pathogenesis of many vitreoretinal disorders. This condition is currently managed by vitrectomy, a routine but invasive surgery which is especially challenging in patients with firm vitreoretinal adhesions. Since 1998, pharmacological...
ORGANISM(S): Hathewaya Histolytica 
2026-02-10 | PXD060529 | panorama
Polydopamine (PDA) is a polymer obtained from the self-polymerization of dopamine monomers; during the synthesis process, spherical nanoparticles are formed (PDA NPs), presenting several interesting properties such as high drug encapsulation capacity, easy and versatile surface modification, ability...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051299 | Pride
Reactive oxygen species (ROS) are active molecules involved in several biological functions. When the production of ROS is not counterbalanced by the action of protective antioxidant mechanisms present in living organisms, a condition of oxidative stress can arise with consequent damage to biologica...
ORGANISM(S): Homo sapiens (Human) 
2022-06-22 | PXD032916 | Pride
The precise control of cell activity is crucial for understanding and potentially treating many disorders. Focusing on neurons and myotubes, recent advancements in nanotechnology have introduced photoresponsive nanoparticles as a novel tool for modulating cell function with high spatial and temporal...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-04-23 | PXD061533 | Pride
Controlled Nutrient Delivery to Pancreatic Islets Using Polydopamine-Coated Mesoporous Silica Nanoparticles
Non-alcoholic fatty liver disease (NAFLD), or hepatic steatosis, has become one of the most common pathologies among liver-related disorders. The rapid accumulation of fat in this organ, and the consequent increment in oxidative stress levels, have been recognized as one of the main factors involved...
ORGANISM(S): Homo sapiens (Human) 
2024-10-02 | PXD046524 | Pride
Mitochondrial disorders are a subset of hereditary diseases characterized by defects in mitochondrial functionality due to mutations in genes in nuclear or mitochondrial DNA. The molecular hallmarks of mitochondrial disorders include a high production of reactive oxygen species (ROS), morphological ...
ORGANISM(S): Homo sapiens (Human) 
2026-07-16 | PXD063824 | Pride
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