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ProteomicsStructure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
Mycobacterium polyketide synthase 13 (Pks13) is a protein complex comprised of a closely symmetric parallel dimer of chains, each encoding several enzymatic and transport functions. This module carries out the condensation of two different very long chain fatty acids to produce mycolic acids that ar...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2023-06-13 | PXD033471 | Pride
Xl-ms Dsso Polyketide synthase pks13 Mycobacterium 
ProteomicsSolution study of a type I polyketide synthase from Mycobacterium tuberculosis: pks13, the condensase of mycolic acids
Background: Among the nineteen polyketide synthases encoded by the genome of Mycobacterium tuberculosis, Pks13 was identified as the condensase required for the final condensation step of two long acyl chains. This leads to mycolic acids, which are essential components of the cell envelope of Cory...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2022-05-11 | PXD029754 | Pride
Polyketide synthases Mycolic acids Bottom up Native ms Mycobacterium tuberculosis Pks13 
UnknownStructure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Not available
S-EPMC10312659 | biostudies-literature
UnknownBiochemical and structural study of the atypical acyltransferase domain from the mycobacterial polyketide synthase Pks13.
Not available
S-EPMC3460465 | biostudies-literature
UnknownSolution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.
Not available
S-EPMC9210659 | biostudies-literature
UnknownStructure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Not available
S-EPMC9900942 | biostudies-literature
UnknownA polyketide macrolactone synthase from the filamentous fungus Gibberella zeae.
Not available
S-EPMC2359803 | biostudies-literature
UnknownIdentification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.
Not available
S-EPMC10683028 | biostudies-literature
UnknownDevelopment of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Not available
S-EPMC5509550 | biostudies-literature
UnknownCrystallization and structure analysis of the core motif of the Pks13 acyltransferase domain from Mycobacterium tuberculosis.
Not available
S-EPMC5944431 | biostudies-literature
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