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ProteomicsRapid Detection of Procalcitonin in septic serum by Immunoaffinity MALDI Chips
PCT concentration in the bloodstream correlates well with sepsis presence and in severe cases increases up to a thousand times from the healthy physiological values in a short time. In this study, we developed a rapid technique for PCT detection by MALDI-MS, that uses in-situ enrichment directly on ...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD035456 | Pride
Immunoaffinity chips Procalcitonin Maldi-tof Sepsis 
ProteomicsCharacterization of ISG65-Cd3 complex
Identification of disulfide bonds of ISG65 protein and hydrogen-deuteium exchange with mass spectrometry for characterization of protein-protein interaction area.
ORGANISM(S): Homo sapiens (Human) Trypanosoma brucei 
2023-05-10 | PXD033606 | Pride
Hydrogen-deuterium exchange Isg65-cd3 complex Mass spectrometry 
ProteomicsFast Fluoroalkylation of Proteins Uncovers Structure and Dynamics of Biological Macromolecules
Stable covalent labeling of proteins in combination with mass spectrometry has been established as a complementary technique to classical structural methods, such as X Ray, NMR, or Cryo-EM used for protein structure determination. Although the current stable covalent labeling techniques enable to mo...
ORGANISM(S): Homo sapiens (Human) 
2021-12-30 | PXD027310 | Pride
Radical labeling Mass spectrometry Protein footprinting Conformational changes Fluoroalkylation Hyperva-lent iodine reagents Protein structure Togni reagents Protein fingerprinting Epitope mapping Protein surface mapping Radicals Proteomics Interactomics Trifluoromethylation 
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