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ProteomicsCo-translational and Post-translational protein myristoylation in HeLa cells
Protein N-myristoylation is a ubiquitous co- and post-translational modification that has been implicated in the development and progression of a range of human diseases. In E. Thinon, R. A. Serwa, et al., Nature Communications 2014, doi:10.1038/ncomms5919, we report the global N-myristoylated prote...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD002687 | Pride
Co-translational modification Post-translational modification Apoptosis Protein myristoylation 
TranscriptomicsTranscription profiling of HHV-6B viral genes from infected human CD4+ cells in the presence of DNA synthesis inhibitor
Transcriptional profiling of viral genes in the presence of DNA synthesis inhibitor.
ORGANISM(S): Homo sapiens 
2009-08-07 | E-MEXP-2130 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human SupT1 cells 6 to 60 hours after HHV-6B infection without inhibitors
Transcriptional profiling of viral genes.
ORGANISM(S): Homo sapiens 
2010-04-05 | E-MEXP-2129 | biostudies-arrayexpress
ProteomicsAMCA chromophore tagging and 351 nm ultraviolet photodissociation enables de novo sequencing of E. coli proteome
Demonstration of novel experimental and computational pipeline for high performance de novo peptide sequencing. E. coli whole cell lysate is carbamylated to block lysine side chains, digested with trypsin (now active only at Arg residues), and N-terminally tagged with the chromophore AMCA. Three tec...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2016-03-10 | MSV000079571 | MassIVE
TranscriptomicsRNAi knock down of heterochromatin protein 1 in male and female Drosophila flies
Drosophila heterochromatin protein 1- HP1 is believed to be involved in active transcription, transcriptional gene silencing, and the formation of heterochromatin2-7. However, little is known about the function of HP1 during development. Using a Gal4-induced RNA interference system, we show that con...
ORGANISM(S): Drosophila melanogaster 
2007-08-01 | E-GEOD-3055 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of post-mortem human brain to investigate gender specific gene expression
Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in bra...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2164 | biostudies-arrayexpress
UnknownSex peptide receptor-regulated polyandry modulates the balance of pre- and post-copulatory sexual selection in Drosophila.
Not available
S-EPMC6336784 | biostudies-literature
ProteomicsPanorama of ancient metazoan macromolecular complexes: Sea urchin
By combining extensive biochemical fractionation with quantitative mass spectrometry, we directly examined the composition of soluble multiprotein complexes among diverse animal models. The project has been jointly supervised by Andrew Emili and Edward M. Marcotte. Project website: http://metazoa.me...
ORGANISM(S): Strongylocentrotus purpuratus (Purple sea urchin) 
2015-06-19 | PXD002325 | Pride
Lc-msms Conservation Metazoan Biofractionation Across species 
TranscriptomicsTranscriptional profiling of a novel pro-angiogenic small molecule phthalimide neovascular factor 1 (PNF1)
We generated the transcriptional regulatory footprint of phthalimide neovascular factor 1 (PNF1)—a novel synthetic small molecule that exhibits significant in vitro endothelial potency and significant in vivo microvascular network expansion—by performing comparative microarray analysis on PNF1-stimu...
ORGANISM(S): Homo sapiens 
2009-07-17 | E-GEOD-17119 | biostudies-arrayexpress
TranscriptomicsGene-expression profile of Id2+ versus Id2KO KLRG1lo cells during infection
CD8+ T cells play a crucial role in the clearance of intracellular pathogens through the generation of cytotoxic effector cells that eliminate infected cells and long-lived memory cells that provide enhanced protection against reinfection. We have previously shown that the inhibitor of E protein tra...
ORGANISM(S): Mus musculus 
2013-03-07 | E-GEOD-41978 | biostudies-arrayexpress
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