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ProteomicsProteomic Blueprint of the Pituitary anterior and posterior lobes for better understanding of the physiology of pituitary gland.
This study provides a comprehensive proteomic analysis of five matched pairs of the anterior and posterior lobe of the pituitary, which was used to study the proteomic signature specific to both anterior and posterior lobes.
ORGANISM(S): Homo Sapiens 
2022-12-06 | PXD029991 | panorama
ProteomicsMass Spectrometry analysis of human matched Anterior and Posterior lobes of Pituitary
This study provides a comprehensive proteomic analysis of five matched pairs of the anterior and posterior lobe of the pituitary, which was used to study the proteomic signature specific to both anterior and posterior lobes. Anterior Lobe n=5 Posterior Lobe n=5 A441 PT441 A442 ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-07 | PXD030235 | Pride
Pituitary Label free quantification lfq Proteomics Obribtrap based mass spectrometery analysis Lc-msms 
TranscriptomicsTranscription profiling of gonadotrope pituitary tumors identifies Growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a Novel Tumor Suppressor in Pituitary Gonadotrope Tumors
Gonadotrope or null cell pituitary tumors present clinically with signs of hypogonadism and hypopituitarism, together with visual disturbances due to mass effects. Since there are no medical therapies, surgery and/or radiation are the only therapeutic options. To identify dysregulated genes and/or...
ORGANISM(S): Homo sapiens 
2011-01-31 | E-GEOD-26966 | biostudies-arrayexpress
ProteomicsUnderstanding early AutoAb signatures in Pituitary Adenomas using CDI HuProt™ (Human Proteome Microarray)
CDI HuProt™ (Human Proteome Microarray), was used to study Pituitary Adenomas PAs (Acromegaly, Cushing's and NFPA) using serum samples, from around 14 individuals (4 Healthy control, 4 Acromegaly, 3 Cushing’s and 3 NFPAs patient samples) were used study their autoantibody profiles. Patient serum sam...
ORGANISM(S): Homo sapiens 
2022-09-30 | E-MTAB-11947 | biostudies-arrayexpress
GenomicsGenetic and epigenetic characterization of posterior pituitary tumors
Genetic and epigenetic characterization of posterior pituitary tumors
PRJNA767426 | ENA
TranscriptomicsSequencing of murine corticotrophs from male and female POMC-GFP mice.
Stress-related illness represents a major burden on health and society. Understanding the molecular mechanisms underlying stress responses is an important step to understand these diseases, and design treatments. Sexual dimorphism in stress responses have been extensively reported, with depression a...
ORGANISM(S): Mus musculus 
2023-05-03 | E-MTAB-12885 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse adult primary neural stem cells when stimulated with the proliferative agent PACAP (pituitary adenylate cyclase-activating polypeptide)
Investigation of transcriptional changes induced in adult primary neural stem cells when stimulated with the proliferative agent PACAP (pituitary adenylate cyclase-activating polypeptide). In addition the data was compared to results obtained from a proliferation control (stimulation with a transmem...
ORGANISM(S): Mus musculus 
2005-05-15 | E-MEXP-322 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat neurointermediate lobe in euhydrated and dehydrated animals
The hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei are important integrative structures that regulate co-ordinated responses to perturbations in cardiovascular homeostasis. Through descending projections from parvocellular neurons to the brainstem, the PVN acts as an autonomic 'p...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3125 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat hypothalamic paraventricular (PVN)nuclei in euhydrated and dehydrated animals
The hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei are important integrative structures that regulate co-ordinated responses to perturbations in cardiovascular homeostasis. Through descending projections from parvocellular neurons to the brainstem, the PVN acts as an autonomic 'p...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3111 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat hypothalamo-neurohypophyseal system in euhydrated and dehydrated animals
The hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei are important integrative structures that regulate co-ordinated responses to perturbations in cardiovascular homeostasis. Through descending projections from parvocellular neurons to the brainstem, the PVN acts as an autonomic 'p...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3110 | biostudies-arrayexpress
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