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ProteomicsA Comparative Proteomic Analysis of Whey Protein from Early, Mid and Late Lactation Stages of Indian Indigenous Breed, MalnadGidda (Bosindicus)
Different lactation stages have marked influence on milk yield, milk constituents and nourishment of the neonates. However, the differential gene expression during different lactation stages in Bosindicus has not been investigated so far. In this study, we carried out high-resolution mass spectromet...
ORGANISM(S): Bos indicus 
2018-02-16 | PXD007655 | Pride
Ultracentrifugation Tmt labeling Isoelectric precipitation Brplc Biomarker 
MetabolomicsDeciphering metabolomic alterations in seminal plasma of crossbred (Bos taurus X Bos indicus) bulls through comparative deep metabolomic analysis
The incidence of sub-fertility is higher in crossbred bulls compared to zebu bulls. In the present study, we analysed the metabolomic profile of seminal plasma from crossbred and zebu bulls and uncovered differentially expressed metabolites between these two breeds. Using a high-throughput LC-MS/MS-...
2021-12-22 | MTBLS1642 | MetaboLights
ProteomicsA proteomic landscape of the spatiotemporal influence of Interleukin-33 (IL-33) in monocytes
Interleukin-33 (IL-33), a member of the IL-1 superfamily cytokines, is an endogenous danger signal and a nuclear-associated cytokine. It is one of the essential mediators of both innate and adaptive immune responses. Aberrant IL-33 signaling has been demonstrated to play a defensive role against var...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD028673 | Pride
Innate immunity Inflammation Cytokines Mass spectrometry Signaling Monocytes 
ProteomicsData-independent acquisition (DIA) based quantitative proteomic analysis of oral cancer tissue samples
Oral cancer ranks as the 7th most common cancer worldwide with an increasing incidence and mortality rate. Currently, immunotherapy has emerged as a promising approach for cancer treatment including in head and neck cancer, characterised by prolonged survival rate. We conducted a data-independent ac...
ORGANISM(S): Homo sapiens (Human) 
2025-06-11 | PXD052432 | Pride
Lc-ms/ms Proteomics Dia-nn Oral cancer Dia Mass spectrometry 
ProteomicsQuantitative proteomics profiling of spermatozoa and seminal plasma reveals proteins associated with semen quality in Bos indicus bulls
Primary aim of the analysis was to identify proteomic differences in the semen samples of Bos indicus that accounts for high or low ERR. This was achieved through tandem mass-tags based quantitative proteomics approach coupled to LC-MS/MS methods. An Orbitrap Fusion Tribrid mass spectrometer (Thermo...
ORGANISM(S): Bos taurus (Bovine) 
2024-07-15 | PXD034096 | Pride
Bos indicus Quantitative proteomics Tmt Spermatozoa Animal reproduction Veterinary research Seminal plasma 
ProteomicsA proteomic landscape of the human cornea
The sclera is white, tough outer covering, known for providing structural support to the eyeball and the intraocular contents. Any abnormality in sclera results in disorders such as conjunctivitis, episcleritis, scleritis and hence a proper investigation will help in preventing the same. In the curr...
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD009261 | Pride
Protein profiling Omics technology Tandem mass spectrometry Protein abundance Eye proteome 
ProteomicsIntegrated multi-omic analysis of M. tuberculosis H37Ra redefines virulence attributes
M. tuberculosis H37Ra, an avirulent tubercle bacillus, is a commonly used model to investigate virulence attenuation in M. tuberculosis. Comparative high-throughput studies have earlier correlated its avirulence to the presence of specific mutations or absence of certain proteins. However, a recent ...
ORGANISM(S): Mycobacterium tuberculosis H37Ra 
2018-10-22 | PXD008555 | Pride
Genome annotation Tuberculosis Virulence attenuation Orbitrap Next-generation sequencing 
ProteomicsProteomic analysis of early salt stress response in root and shoot of rice seedlings
To elucidate early stress response signalling networks evolved in rice, we have demonstrated the comparative proteome analysis of 10-day-old IR-64 rice seedlings (Oryza sativa L. cv. IR-68) subjected to 200 mM NaCl stress for 6 hours and control condition
ORGANISM(S): Oryza sativa (Rice) 
2026-04-15 | PXD024902 | Pride
Tmt Salt stress Rice Orbitrap fusion 
ProteomicsExploring molecular dynamics indicators associated with reproductive performance of Bos indicus cattle in plasma samples through data-independent acquisition mass spectrometry
Aim of the study was to profile the blood plasma proteome of healthy Bos indicus cattle and use it as a baseline against which to compare different conditions in Bos indicus cattle, such as disease, reproduction associated proteins and pregnancy specific proteins etc. Data-independent acquisition (D...
ORGANISM(S): Bos taurus (Bovine) 
2024-07-15 | PXD034103 | Pride
Lc-ms/ms-dia Bos indicus Quantitative proteomics Plasma Animal reproduction Diary research 
ProteomicsQuantitative phosphoproteomics reveals diverse stimuli activate distinct signaling pathways during neutrophil activation
Neutrophils play an active role in acute and chronic inflammation by exhibiting functional heterogeneity. Besides beneficial role in acute infections to eliminate pathogens, neutrophils also contribute to pathogenesis of diseases associated with sterile inflammation including vascular disorders, aut...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD029046 | Pride
Infections Neutrophils Hyperglycemia Type 2 diabetes Homocysteine 
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