Sort   by:  
 Page size 
ProteomicsStructure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex, and the Regulation of Transcription
MedPIC: Crosslinking-MS of 54 subunit pre-initiation complex from yeast. MedPolII: Crosslinking-MS of 33 subunit Mediator + polII complex from yeast.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2016-08-02 | MSV000080013 | MassIVE
ProteomicsStructural inventory of native ribosomal ABCE1-43S pre-initiation complex
In eukaryotic translation, the termination and recycling phases are linked to subsequent initiation by persistence of several factors. These comprise the large eIF3 complex, eIF3j (Hcr1 in yeast) and the ATP-binding cassette protein ABCE1 (Rli1 in yeast). The ATPase is mainly active as a recycling f...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-10-16 | PXD020849 | Pride
Abce1 Ribosome Yeast Abc-proteins Translation initiation 
ProteomicsCrosslinking mass spectrometry of yeast Pol I pre-initiation complex
In eukaryotic cells, ribosomal RNA is transcribed by RNA polymerase I (Pol I). To initiate transcription, Pol I requires the assembly of a multi-subunit pre-initiation complex (PIC). In yeast, the minimal PIC includes Pol I, the transcription factor Rrn3 and Core Factor (CF) composed of subunits Rrn...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-31 | PXD006510 | Pride
Pol i Transcription Core factor Pol i pre-initiation complex Crosslinking Ribosomal rna 
GenomicsTAF4 promotes pre-initiation complex formation and HNF4A occupancy of regulatory elements required to activation post-natal gene expression programme in hepatocytes (ChIP-seq)
The nuclear receptor HNF4A regulates embryonic and post-natal hepatocyte gene expression. Using hepatocyte-specific inactivation in mice, we show that the TAF4 subunit of TFIID acts as a cofactor for HNF4A in vivo and that HNF4A interacts directly with the TAF4-TAF12 heterodimer in vitro. In vivo, T...
ORGANISM(S): Mus musculus 
2014-09-25 | E-GEOD-57807 | biostudies-arrayexpress
TranscriptomicsTAF4 promotes pre-initiation complex formation and HNF4A occupancy of regulatory elements required to activation post-natal gene expression programme in hepatocytes (RNA-seq)
The nuclear receptor HNF4A regulates embryonic and post-natal hepatocyte gene expression. Using hepatocyte-specific inactivation in mice, we show that the TAF4 subunit of TFIID acts as a cofactor for HNF4A in vivo and that HNF4A interacts directly with the TAF4-TAF12 heterodimer in vitro. In vivo, T...
ORGANISM(S): Mus musculus 
2014-09-25 | E-GEOD-57712 | biostudies-arrayexpress
GenomicsDephosphorylation of the pre-initiation complex during S-phase is critical for origin firing dynamics
Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing dynamics
PRJNA774064 | ENA
GenomicsRPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
PRJNA797170 | ENA
TranscriptomicsGlucose depletion inhibits translation initiation in yeast - transcription profiling
This is a transcription profiling study on yeast undergoing glucose depletion. It reveals that glucose depletion inhibits translation initiation in a mechanism involving eIF4A loss and 48S pre-initiation complex accumulation, while the pentose phosphate pathway is co-ordinately up-regulated
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-11 | E-MEXP-3037 | biostudies-arrayexpress
TranscriptomicsChromatin immunopreciptiation to determine the genome wide locatio of different components of the RNA polymerase II preinitiation complex in yeast
Genome wide location of different components of RNA polymerase II preinitiation complex in yeast S.cerevisiae
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-01 | E-MEXP-1502 | biostudies-arrayexpress
ProteomicsStructural basis of the SWI/SNF-bound transcription pre-initiation complex
DSSO crosslinking of SwiSnf + Mediator + Pre-initiation Complex. Two replicate experiments starting with 300 ug of protein and 6 mM DSSO. Crosslinked peptides were fractionated by size-exclusion chromatography (SEC) and 8 SEC were analyzed by LC-MS on an Orbitrap Exploris 480 instrument. The first s...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2025-05-14 | MSV000097892 | MassIVE
Sort   by:  
 Page size