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TranscriptomicsTranscription profiling of human hypothalamic hamartomas (HH) obtained from patients with or without precocious puberty (CPP)
Hypothalamic hamartomas (HHs) are congenital lesions of the neuroendocrine brain composed of neurons and astroglia. Frequently, HHs are associated with central precocious puberty (CPP) and/or gelastic seizures. Because HHs might express genes similar to those required for the initiation of normal pu...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7142 | biostudies-arrayexpress
TranscriptomicsMethylome analysis in girls with idiopathic central precocious puberty
The present study aims to investigate changes in genomic DNA methylation profiles associated with pubertal onset analysing human peripheral blood leucocytes from three different groups of subjects: central precocious puberty (CPP), healthy prepubertal girls matched by age (CTPP), and healthy puberta...
ORGANISM(S): Homo sapiens 
2025-01-10 | E-MTAB-13950 | biostudies-arrayexpress
ProteomicsProteomic Analysis of Mkrn3 WT vs KO mouse brain
Mutations in the E3 ubiquitin ligase Mkrn3 are associated with precocious puberty in humans. In order to determine the targets of Mkrn3, we performed a TMT-based proteomic analysis of Mkrn3 WT vs KO mouse brains.
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD027220 | Pride
Mouse Brain Tmt E3 ubiquitin ligase Precocious puberty 
ProteomicsIntegrated Analysis of Proteomics and Metabolomics in Girls with Central Precocious Puberty
Central precocious puberty (CPP) is a multifactorial and complex condition. Traditional studies focusing on a single indicator cannot always elucidate this panoramic condition but these may be revealed by using omics techniques. Proteomics and metabolomics analysis of girls with CPP were compared to...
ORGANISM(S): Homo Sapiens 
PXD035132 |
GenomicsAccelerated passage of gene-modified monkeys by hormone-induced precocious puberty
Accelerated passage of gene-modified monkeys by hormone-induced precocious puberty
PRJNA705598 | ENA
UnknownPrecocious puberty in patients with Pompe disease.
Not available
S-EPMC10465365 | biostudies-literature
UnknownGut microbiota alterations modulate high-fat diet-induced precocious puberty.
Not available
S-EPMC12403903 | biostudies-literature
UnknownAssociation between MKRN3 and LIN28B polymorphisms and precocious puberty.
Not available
S-EPMC6062980 | biostudies-literature
UnknownDietary pattern and precocious puberty risk in Chinese girls: a case-control study.
Not available
S-EPMC10829199 | biostudies-literature
UnknownGut microbiota-metabolite interactions meditate the effect of dietary patterns on precocious puberty.
Not available
S-EPMC11112371 | biostudies-literature
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