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TranscriptomicsQuantitative time-course profiling of Plasmodium falciparum transcripts and proteins throughout the 48-hour intraerythrocytic developmental cycle
Quantitative studies of the P. falciparum transcriptome have shown that the tightly controlled progression of the parasite through the intraerythrocytic developmental cycle (IDC) is accompanied by a continuous gene expression cascade where most expressed genes exhibit a single transcriptional peak. ...
ORGANISM(S): Plasmodium falciparum 
2011-06-07 | E-GEOD-24416 | biostudies-arrayexpress
TranscriptomicsComparison of relative transcript and protein abundance in Plasmodium falciparum schizont stage parasites
Background: Malaria is a one of the most important infectious diseases and is caused by parasitic protozoa of the genus Plasmodium. Previously, the quantitative characterization of the P. falciparum transcriptome demonstrated that the strictly controlled progression of these parasites through their ...
ORGANISM(S): Plasmodium falciparum 
2010-05-05 | E-GEOD-13251 | biostudies-arrayexpress
TranscriptomicsNew insights into the Plasmodium vivax transcriptome using RNA-seq
Transcription profile of the Plasmodium vivax intraerythrocytic cycle Total RNA in Plasmodium vivax strain at every 6 hour of intraerythrocytic cycle using RNA-seq
ORGANISM(S): Plasmodium vivax 
2016-02-11 | E-GEOD-61252 | biostudies-arrayexpress
ProteomicsCohesin is involved in transcriptional repression of invasion-related genes
The most virulent human malaria parasite, Plasmodium falciparum, has a complex life cycle between its human host and mosquito vector. Each stage is driven by a specific transcriptional program, but with a relatively high ratio of genes to specific transcription factors, it is unclear how genes are a...
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD035225 | Pride
Plasmodium Smc3 Cohesin 
TranscriptomicsPlasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures
The purpose of this reasearch is to identify and evaluate the global gene expression of Plasmodium knowlesi blood-stage parasites and specifically compare the gene expression profiles of samples derived from ex vivo versus long-term in vitro cultures. For ex vivo samples, a rhesus monkey was infecte...
ORGANISM(S): Plasmodium knowlesi 
2015-06-08 | E-GEOD-62886 | biostudies-arrayexpress
TranscriptomicsCharacterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS)
The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species. Despite comprising up to 5% of the parasite genome, little is known about the functions of the proteins encoded by pir genes. P. chabaudi causes chronic inf...
ORGANISM(S): Plasmodium chabaudi chabaudi 
2012-05-31 | E-GEOD-33333 | biostudies-arrayexpress
UnknownCohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite
Not available
S-SCDT-10_15252-EMBR_202357090 | biostudies-other
ProteomicsCytosine methylation of tRNA in Plasmodium falciparum disrupts translational homeostasis to prime for sexual commitment
Malaria parasites have evolved a well-adjusted developmental program to progress through the complex life cycle in the human and mosquito host. Here we identify cytosine methylation of tRNAAsp (GTC) as being critical to maintain stable protein synthesis under cellular stress. Using conditional knock...
ORGANISM(S): Plasmodium falciparum (isolate 3D7) 
2022-02-13 | PXD024769 | Pride
Epitranscriptomics Dmt2 Trna Plasmodium 
UnknownThe DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.
Not available
S-EPMC6181207 | biostudies-literature
UnknownGlobal disparities in SARS-CoV-2 genomic surveillance.
Not available
S-EPMC9667854 | biostudies-literature
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