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MetabolomicsMg2+ in drinking water exacerbates Salmonella Typhimurium T6SS-mediated intestinal bacterial competition through affecting metabolic reprogramming

By establishing a model of enteritis in mice infected with Salmonella Typhimurium, this study investigates the effects of ion concentration in drinking water on intestinal metabolites and microbiota structure in mice, as well as its influence on pathogen susceptibility and the host-patho...

2025-12-30 | MTBLS12690 | MetaboLights
ProteomicsMitochondrial protein interaction landscape of SS-31
SS-31 is a synthetic peptide that improves mitochondrial function and is currently undergoing clinical trials for treatments of heart failure, primary mitochondrial myopathy, and other mitochondrial diseases. SS-31 interacts with cardiolipin which is abundant in the inner mitochondrial membrane, but...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-12 | PXD019484 | Pride
Cross-linking mass spectometry Mitochondria Ss-31 Mouse Elamipretide 
TranscriptomicsPrimary Sjogren's syndrome study
The objective of the study was to identify gene expression signatures in minor salivary glands (MSGs) from patients with primary Sjogren's syndrome (SS). METHODS: A 16K complementary DNA microarray was used to generate gene expression profiles in MSGs obtained from 10 patients with primary SS and 10...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-MTAB-2073 | biostudies-arrayexpress
Genomics
BAFF SNPs and fatigue in primary SS patients
PRJEB51100 | ENA
GenomicsBulk RNA sequencing in minor salivary glands of Brazilian patients with primary Sjögren’s syndrome (SS) and healthy volunteers
Bulk RNA sequencing in minor salivary glands of Brazilian patients with primary Sjögren’s syndrome (SS) and healthy volunteers
PRJNA647889 | ENA
UnknownAutoantibodies identify primary Sjogren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B.
Not available
S-EPMC10546962 | biostudies-literature
TranscriptomicsMicroarray analysis of minor salivary glands from patients with primary Sjögren’s syndrome (SS) or non-SS
Objective. A variety of chemokines contribute the pathogenesis of Sjögren’s syndrome (SS). However, the comprehensive analysis as for clinically potent ckemokines in SS has not been performed. In this study, focusing on CXC chemokines, we investigated the precise molecular mechanism and the clinical...
ORGANISM(S): Homo sapiens 
2016-08-31 | GSE80805 | GEO
GenomicsBAFF SNPs and fatigue in primary SS patients
An investigation into the association of BAFF variants with fatigue development in the setting of primary Sjogren's Syndrome (SS). Analysis performed in a cohort of 199 Greek primary SS patients, in a validation cohort of 62 Dutch primary SS patients and in a cohort of 52 Greek Multiple Sclerosis (M...
ORGANISM(S): Homo Sapiens 
2022-02-25 | PRJEB51100 | EVA
ProteomicsGel-Free Proteomics of Sjögren’s Syndrome patient saliva
Sjögren's Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. It can be defined as primary SS (pSS) or associated/secondary SS (sSS) if combined with another systemic autoimmune disease. Ident...
ORGANISM(S): Homo sapiens (Human) 
2021-06-09 | PXD025434 | Pride
Sjögren’s syndrome Sds-page Secondary ss Primary ss Gel-free Saliva 
ProteomicsGel-based proteomics of Sjögren’s Syndrome patient saliva
Sjögren's Syndrome (SS) is an autoimmune exocrinopathy characterized by the progressive damage of salivary and lacrimal glands associated with lymphocytic infiltration. It can be defined as primary SS (pSS) or associated/secondary SS (sSS) if combined with another systemic autoimmune disease. Ident...
ORGANISM(S): Homo sapiens (Human) 
2021-06-09 | PXD025463 | Pride
Sjögren’s syndrome Sds-page Secondary ss Primary ss Gel-free Saliva 
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