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ProteomicsCharacterization of the regulatory AAA-ATPase subunit Rpt3 in Plasmodium berghei as an activator of Protein Phosphatase 1
The 26S proteasome is the main proteolytic machine involved in protein degradation, contributing to homeostasis or stress response of eukaryotic cells. This macromolecular complex, consisting of a 20S core particle assembled with one or two 19S regulatory particles, is highly regulated by phos-phory...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-03 | PXD044616 | Pride
Proteasome Rpt3 Protein phosphatase 1 19s regulatory particle Lcms Plasmodium 
ProteomicsEffect of proteasome inhibition on total and poly-ubiquitylated proteomes of human A549 lung adenocarcinoma cells in different proliferation states
Cellular stress responses are crucial for survival in sub-optimal conditions, and almost invar-iably involve proteome-wide alterations at the levels of protein abundance and post-translational modification with poly-ubiquitin chains (poly-ubiquitylation). However, most of our understanding of human ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-08 | PXD067220 | Pride
Human Proteostasis Insoluble Lung Cancer Ubiquitin Aggregate Lc-msms Bortezomib Stress Senescence Epithelia Pro-teasome 
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