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ProteomicsMonitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level
Protein phosphorylation, one of the most common and important modifications of acute and reversible regulation of protein function, plays a dominant role in almost all cellular processes. These signaling events regulate cellular responses including proliferation, differentiation, metabolism, surviva...
ORGANISM(S): Homo sapiens (Human) 
2015-11-09 | PXD002436 | Pride
Proteomics thiophosphorylation signaling 
UnknownMonitoring Cellular Phosphorylation Signaling Pathways into Chromatin and Down to the Gene Level.
Not available
S-EPMC4813704 | biostudies-literature
ProteomicsPhosphoproteomics of FGF signaling in Chrondrocytes
To understand the determinants of chondrocyte FGF inhibitory response we sought to identify the unique set of proteins whose phosphorylation status is changed upon FGF treatment. RCS (Rat ChondroSarcoma) (RCS) cells were used for our experiments as a well-accepted model of proliferative chondrocytes...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2016-10-20 | MSV000080259 | MassIVE
ProteomicsIntegrated Phosphoproteomics of Theileria annulata-Infected Cells: Unveiling Host and Parasite Kinase Networks and Signaling Pathways
This study employs comparative phosphoproteomics to investigate the changes in protein phosphorylation (post-translational modifications) induced by Theileria annulata infection in host cells. Three groups are analyzed: bovine lymphocytes infected with T. annulata, uninfected control lymphocytes, an...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Theileria Annulata (ncbitaxon:5874) 
2024-06-10 | MSV000094978 | MassIVE
ProteomicsAnalysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma - Thiophosphorylation
Apicomplexan parasites use Ca2+-regulated exocytosis to secrete essential virulence factors from specialized organelles called micronemes. Ca2+-dependent protein kinases (CDPKs) are required for microneme exocytosis; however, the molecular events that regulate trafficking and fusion of micronemes wi...
ORGANISM(S): Toxoplasma gondii GT1 
2023-10-18 | PXD039431 | Pride
T. gondii Lc-msms Vesicular trafficking Signaling 
ProteomicsDUX4 expression activates JNK and p38 MAP kinases in myoblasts
Facioscapulohumoral muscular dystrophy (FSHD) is caused by misexpression of the DUX4 transcription factor in skeletal muscle that results in transcriptional alterations, abnormal phenotypes, and cell death. To gain insight into the kinetics of DUX4-induced stresses, we activated DUX4 expression in m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-07-05 | MSV000089812 | MassIVE
ProteomicsPhosphoproteome of RAW264.7 cells infected with quorum sensing ON and OFF Group A Strep
Phosphoproteome of RA264.7 macrophages 30m post infection with quorum sensing ON or OFF or both Streptococcus pyogenes (Group A Strep), or uninfected. Available are peak lists, .raw files, and processed and quantified results analyzed via Comet.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-01-22 | MSV000096914 | MassIVE
ProteomicsComprehensive spectral library from the pathogenic bacterium Streptococcus pneumoniae with focus on phosphoproteins
In this study, a comprehensive spectral library for S. pneumoniae with an emphasis on phosphopeptide spectra was compiled. In total, 76% of the theoretical S. pneumoniae proteins were stored in a spectral library. Additionally, in combination with classical database search algorithms and the spectra...
ORGANISM(S): Streptococcus Pneumoniae D39 
MSV000084269 | MassIVE
ProteomicsHuman hypertrophic cardiomyopathy cardiac tissue phosphoproteomics
This study used TMT-pro method to look for phosphoproteomic differences in heart tissue of patients with hypertrophic cardiomyopathy and controls
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-28 | MSV000091822 | MassIVE
ProteomicsScion-rootstock interaction and tolerance to cadmium toxicity in juvenile Theobroma cacao plants
The main objective of this work was to evaluate the toxicity of Cd, in different genotypes of T. cacao, in scion-rootstock combinations (CCN 51-BN 34, CCN 51-PS 1319, CCN 51-PH 16, CCN 51-CCN 51), grown in soil with 150 mg Cd kg-1 soil, together with the control treatment (without addition of Cd in ...
ORGANISM(S): Theobroma Cacao 
2022-03-12 | MSV000089048 | MassIVE
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