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Proteomicsphotoactivation-dependent proximity labeling (PDPL) MS
we report a photoactivation-dependent proximity labeling (PDPL) method designed by genetically attaching photosensitizer protein miniSOG to a protein of interest (POI). Triggered by blue light, singlet oxygen is generated, enabling temporally-resolved chemical probe labeling.
ORGANISM(S): Homo Sapiens 
2022-06-22 | PXD034811 |
GenomicsProximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+ T cell response
Proximity-dependent labeling identifies dendritic cells that prime the antitumor CD4+ T cell response
PRJNA1151000 | ENA
GenomicsDirected evolution improves the catalytic efficiency of APEX2-mediated proximity-dependent RNA labeling
Directed evolution improves the catalytic efficiency of APEX2-mediated proximity-dependent RNA labeling
PRJNA1090511 | ENA
ProteomicsBioorthogonal Photocatalytic Proximity Labeling in Primary Living Samples
In situ profiling of subcellular proteomic networks in primary and living systems, such as primary cells from native tissues or clinic samples, is crucial for the understanding of life processes and diseases, yet challenging for the current proximity labeling methods (e.g., BioID, APEX) due to their...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-05-24 | PXD045791 | Pride
Proximity labeling Mitochondria Bioorthogonal chemistry Photocatalysis 
ProteomicsCilia-iAPEX proximity labeling proteomics
iAPEX-based proximity labeling for proteomic profiling of primary cilia of different cell types
ORGANISM(S): Mus musculus (Mouse) 
2025-09-19 | PXD060138 | Pride
Proximity labeling Apex Tmt Primary cilia 
GenomicsProfiling stress-triggered RNA condensation with photocatalytic proximity labeling
Profiling stress-triggered RNA condensation with photocatalytic proximity labeling
PRJNA925537 | ENA
ProteomicsMapping the DPP9 Interactome by Proximity Labeling
Dipeptidyl peptidase 9 (DPP9) is an amino peptidase with the unusual ability to cleave a peptide bond post-proline. Its function affects immunity, DNA-repair, cell signaling, memory and neonatal survival; its dysregulation is linked to cancer and immune-related disorders. While most studies focus on...
ORGANISM(S): Homo sapiens (Human) 
2026-08-31 | PXD067345 | Pride
Proximity labeling Dpp9 Turboid 
ProteomicsCell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum
The vertebrate brain consists of diverse neuronal types, classified by distinct anatomy and function, along with divergent transcriptomes and proteomes. Defining the cell-type specific neuroproteome is important for understanding the development and functional organization of neural circuits. This t...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-10 | PXD022335 | Pride
Striatum Proximity labeling Apex2 Neurproteomics 
ProteomicsLeveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
Protein-protein interactions play an important biological role in every aspect of cellular homeostasis and functioning. Proximity labeling mass spectrometry-based proteomics overcomes challenges typically associated with other methods, and has quickly become the current state-of-the-art in the field...
ORGANISM(S): Homo sapiens (Human) 
2024-06-10 | PXD046413 | Pride
Bioid Sars-cov-2 nsp7 Turboid Proximity labeling Gr Sars-cov-2 n 
ProteomicsLeveraging a self-cleaving peptide for tailored control in proximity labeling proteomics
Protein-protein interactions play an important biological role in every aspect of cellular homeostasis and functioning. Proximity labeling mass spectrometry-based proteomics overcomes challenges typically associated with other methods, and has quickly become the current state-of-the-art in the field...
ORGANISM(S): Homo sapiens (Human) 
2024-06-10 | PXD046414 | Pride
Bioid Sars-cov-2 nsp7 Turboid Proximity labeling Gr Sars-cov-2 n 
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