Proximity dependent labelling

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CHEBI ID

CHEBI:77846 (1)
CHEBI:25801 (1)
CHEBI:17797 (1)
CHEBI:16132 (1)
CHEBI:28997 (1)
CHEBI:37574 (1)
CHEBI:16298 (1)
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Metabolite Name

Uracil M+4 (1)
Uracil M+3 (1)
Uracil M+2 (1)
Uracil M+1 (1)
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Adenine M+5 (1)
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Adenosine M+6 (1)
Adenosine M+5 (1)
Adenosine M+4 (1)
Adenosine M+3 (1)
Adenosine M+2 (1)

First Public Date

2026 (2)
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2020 (1)

Study type

Transcription profiling by array (39)
ChIP-chip by tiling array (6)
Methylation profiling by array (6)
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Unknown experiment type (3)
RNA-seq of coding RNA (3)
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2010 (13)
2012 (11)
2014 (10)
2021 (6)
2016 (6)
2011 (6)
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2013 (4)
2007 (4)
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2008 (3)
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Lab affiliation

Dr. Matthias Gstaiger ETH Zürich Institute of Molecular Systems Biology Otto-Stern-Weg 3 8093 Zürich Switzerland (5)
ETH Zürich Institute of Molecular Systems Biology HPM F43 Otto-Stern-Weg 3 8093 Zürich Switzerland (5)
Basic Immune System of Plants / Protein Mass Spectrometry Max Planck Institute for Plant Breeding Research Carl-von-Linne-Weg 10, 50829 Cologne, Germany (4)
ETHZ IMSB (4)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA (3)
Institute for Genetics, University of Cologne, 50674 Cologne, Germany (3)
Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland (3)
Department of Agronomy Iowa State University (2)
Department of Biology, University of Fribourg, 1700 Fribourg, Switzerland (2)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (2)
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, 7610001, Israel (2)
Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, United Kingdom (2)
Faculty of Biology, Medicine & Health, Manchester Cell-Matrix Centre, Manchester Academic Health Science Centre, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, United Kingdom (2)
Koç University, Department of Molecular Biology and Genetic Cell Biology Lab head (2)
1. Institute of Physiology, University Clinics and Faculty of Medicine. University of Cologne, Germany 2. Center for Molecular Medicine (CMMC), University of Cologne. Germany 3. Institute of Biochemistry and Molecular Biology, University Clinics and Faculty of Medicine, Heinrich-Heine University Düsseldorf, Germany (1)
Assistant Professor at the School of Biomedical Sciences and Department of Pathology, The University of Hong Kong (1)
Assistant Professor at the School of Biomedical Sciences and Department of Pathology, The University of Hong Kong, Hong Kong (1)
Bernhard Nocht Institute for Tropical Medicine (1)
Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany (1)
Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt am Main, Germany (1)
CSSB Centre for Structural Systems Biology c/o Deutsches Elektronen-Synchrotron DESY Notkestraße 85, Building 15 D-22607 Hamburg (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Cambridge Institute for Medical Research, University of Cambridge, UK (1)
Cell Signalling & Proteomics Group, Barts Cancer Institute, Queen Mary University of London, London, UK (1)
Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, University of Köln, Köln, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany (lab head) (1)
Chair of Microbiology Biocenter, University of Würzburg D-97074 Würzburg, GERMANZ (1)
Clinical Biochemistry, Cambridge Institute for Medical Research, University of Cambridge, UK (1)
Copenhagen Plant Science Center, Department of Plant & Environmental Sciences, University of Copenhagen, Frederiksberg C, 1871, Denmark (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Core Facility for Mass Spectrometry & Proteomics Center for Molecular Biology of Heidelberg University Heidelberg, Germany (1)

Tags

xref:PubMed:32179799 (1)
xref:PubMed:38721779 (1)
xref:PubMed:41926228 (1)

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Bioorthogonal masked acylating agents for proximity-dependent RNA labelling.

Not available

S-EPMC11613155 | biostudies-literature

Engineering of TurboID-Wingless for the identification of Wingless interactors through in vivo proximity labelling

Wnt signalling coordinates growth and cell fate decisions during development and mis-regulation of Wnt signalling in adults is associated with a range of conditions, including cancer and neurogenerative diseases. Therefore, means of modulating Wnt proteins and/or cofactors could have significant the...

ORGANISM(S): Drosophila melanogaster (Fruit fly)

2026-08-13 | PXD051416 | Pride

Proximity-dependent biotin labelling reveals CP190 as an EcR/Usp molecular partner.

Not available

S-EPMC7075897 | biostudies-literature

Proximity-dependent biotin labelling in yeast using the engineered ascorbate peroxidase APEX2.

Not available

S-EPMC5290329 | biostudies-literature

Proximity proteomics reveals UCH-L1 as an essentialregulator of NLRP3-mediated IL-1β production in humanmacrophages and microglia

Activation of the NACHT, LRR family pyrin domain containing 3 (NLRP3) inflammasome complex is an essential innate immune signalling mechanism. To reveal how NLRP3 inflammasome assembly and activation are controlled, in particular by components of the ubiquitin system, proximity labelling, affinity p...

ORGANISM(S): Homo sapiens (Human)

2024-04-24 | PXD045862 | Pride

Affinity purification-mass spectrometry Apex2 proximity labelling Nlrp3 inflammasome

In vivo proteomic mapping through GFP-directed proximity-dependent biotin labelling in zebrafish.

Not available

S-EPMC7906605 | biostudies-literature

Pupylation-based proximity labelling reveals regulatory factors in cellulose biosynthesis in Arabidopsis

We introduce pupylation-based proximity labelling (PUP-IT) as a tool for protein interaction detection in plant biology. We show that PUP-IT readily confirmed and extended protein interactions for several known protein complexes, across different types of plant systems.

ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Nicotiana tabacum (Common tobacco)

2025-01-10 | PXD048346 | Pride

Pup-it Proximity labelling

BioID proximity proteomics of wild-type and ΔPDZ DVL2 in HEK293 Flp-In T-REx cells

This dataset supports a study investigating how the PDZ domain of Dishevelled-2 (DVL2) specifies β-catenin-independent Wnt signalling outputs. BioID proximity labelling was performed in HEK293 Flp-In T-REx cells stably expressing BirA*-tagged wild-type DVL2 or a matched DVL2 mutant lacking the PDZ d...

ORGANISM(S): Homo sapiens (Human)

2026-09-12 | PXD079793 | Pride

Bioid proximity labelling proximity proteomics dvl2 dishevelled pdz domain daple girdin girdin-l wnt signalling wnt5a primary cilia basal body pdz-pbm interaction lc-ms/ms bottom-up proteomics data-dependent acquisition hek293 flp-in t-rex

ASAP-ID: Proximity labelling with small tags

Biotinylation-based proximity labelling methods are valuable for discovering protein-protein interactions within cellular systems. However, one limitation of these approaches is that most require fusing the target protein with the enzyme that biotinylates nearby proteins (i.e., TurboID or APEX2), wh...

ORGANISM(S): Homo sapiens (Human)

2026-09-07 | PXD066625 | Pride

Human Lc-ms/ms

Interactome of CFTR using Apex and TurboID proximity labelling

The proteins interacting with CFTR and its mutants have been intensively studied using different experimental approaches, enabling to better understand the cellular processes leading to proper protein folding, routing to the plasma membrane, recycling, activation and degradation. Recently, several s...

ORGANISM(S): Homo sapiens (Human)

2022-10-14 | PXD035184 | Pride

Apex Turboid Kcnk3 Cftr Interactome

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