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ProteomicsMBD2 modulates heterochromatin architecture and composition
Heterochromatin (HC) is essential for nuclear integrity, genome stability, and gene regulation with pericentric heterochromatin (PCH) playing a key role. However, the mechanisms governing PCH compartmentalization remain poorly understood. Recent studies suggest that phase separation (PS) underlies t...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-29 | PXD055626 | Pride
Mice brain Dia-ms Mbd2 Pericentric heterochromatin Alphafold server Nuclear fractionation Ps prediction tools Phase separation 
UnknownComputer-aided pattern scoring (C@PS): a novel cheminformatic workflow to predict ligands with rare modes-of-action.
Not available
S-EPMC11421111 | biostudies-literature
TranscriptomicsA genomic classifier improves prediction of metastatic disease within 5 years after surgery in node-negative high-risk prostate cancer patients managed by radical prostatectomy without adjuvant therapy
To determine whether adding Decipher to standard risk stratification tools (CAPRA-S and Stephenson nomogram) improves accuracy in prediction of metastatic disease within 5 years after surgery in men with adverse pathologic features after RP. The study population consisted of 182 patients selected fr...
ORGANISM(S): Homo sapiens 
2014-11-21 | E-GEOD-62667 | biostudies-arrayexpress
TranscriptomicsDevelopment and Validation of a Novel Molecular Biomarker Diagnostic Test for the Early Detection of Sepsis
Introduction: Sepsis is a complex immunological response to infection characterized by early hyperinflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on ...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28750 | biostudies-arrayexpress
UnknownImproved Prediction of Ligand-Protein Binding Affinities by Meta-modeling.
Not available
S-EPMC11632770 | biostudies-literature
UnknownPartner-specific prediction of RNA-binding residues in proteins: A critical assessment.
Not available
S-EPMC6389706 | biostudies-literature
UnknownRefining Drug-Induced Cholestasis Prediction: An Explainable Consensus Model Integrating Chemical and Biological Fingerprints.
Not available
S-EPMC12152943 | biostudies-literature
UnknownPrediction of harmful variants on mitochondrial genes: Test of habitat-dependent and demographic effects in a euryhaline fish.
Not available
S-EPMC5468147 | biostudies-literature
UnknownExternal validation of a surgical mortality risk prediction model for inpatient noncardiac surgery in an Australian private health insurance dataset.
Not available
S-EPMC9804688 | biostudies-literature
UnknownAdvancements in drug discovery: integrating CADD tools and drug repurposing for PD-1/PD-L1 axis inhibition.
Not available
S-EPMC11755407 | biostudies-literature
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