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The protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identified as an important oncogene with roles in promoting cell proliferation, survival, migration, invasion, and metastasis. However, little is currently known about the signaling pathways through which it mediates its effects...
ORGANISM(S): Homo sapiens 
The multifunctional protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identified as an important oncogene with roles in promoting cell proliferation, survival, migration, invasion, and metastasis. However, little is currently known about the signaling pathways through which it medi...
ORGANISM(S): Homo sapiens 
PTP4A1 alleviates angiotensin II-induced aortic aneurysmal lesions by regulating immature mural neovascularisation
We show that silencing of tyrosine phosphatase PTP4A1 attenuates pro-fibrotic TGFb signaling in human dermal fibroblasts
ORGANISM(S): Homo sapiens 
2017-09-12 | GSE102864 | GEO
The subcellular localization of proteins can be highly dynamic and regulated by post-translational modifications. Farnesylation is a lipid modification that enables anchoring of proteins to cellular membranes, and thus, spatially resolved signaling and activity. Due to the importance of farnesylatio...
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD050446 | Pride
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