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ProteomicsA conserved cysteine-based redox mechanism sustains TFEB/HLH-30 activity under persistent stress
Mammalian TFEB and TFE3, as well as their ortholog in C. elegans HLH-30, play an important role in mediating cellular response to a variety of stress conditions, including nutrient deprivation, oxidative stress and pathogen infection. In this study we identify a novel mechanism of TFEB/HLH-30 regula...
ORGANISM(S): Homo sapiens (Human) 
2021-01-22 | PXD022258 | Pride
Hlh-30 Tfeb Glutathionylation Tfe3 Lysosomes 
ProteomicsQuantitative proteomics analysis of WT and tfeb-tfe3s triple knock-out zebrafish adult liver and embryos at 5 days post fertilization
The transcription factors tfeb and tfe3 belong to the MiT/TFE gene family and are known as master regulators of lysosomal function and autophagy. In normal conditions, they are sequestered in the cytosol of the cells and their nuclear translocation is finely regulated in response to a huge array of ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-05-20 | PXD056508 | Pride
Zebrafish adult liver Tmt-multiplex labeling Zebrafish embryos Lc-ms/ms 
UnknownDetection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA.
Not available
S-EPMC9338264 | biostudies-literature
UnknownAssociation Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism.
Not available
S-EPMC8649245 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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