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TranscriptomicsEffects of extensive fasting and subsequent feeding on hepatic transcription
Temporally restricted feeding has a profound effect on the circadian clock. Fasting and feeding paradigms are known to influence hepatic transcription. This dataset shows the dynamic effects of refeeding mice after a 24hour fasting period. Mice were entrained for two weeks under ad libitum access to...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13063 | biostudies-arrayexpress
TranscriptomicsEffects of extensive fasting on hepatic transcription
Temporally restricted feeding has a profound effect on the hepatic circadian clock. While the circadian clock is largely unaffected by by extensive fasting, many transcripts are known to be affected by a fasting paradigm. This dataset shows the effect of extensive fasting on dynamic gene expression ...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13064 | biostudies-arrayexpress
TranscriptomicsThe effects of temporally restricted feeding on hepatic gene expression
Temporally restricted feeding is known to impact the circadian clock. This dataset shows the effects of temporally restricted feeding on the hepatic transcriptome. C57/B6 mice were entrained for two weeks to a temporally restricted feeding schedule. Food was made available only between ZT(CT)1 and Z...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13060 | biostudies-arrayexpress
TranscriptomicsThe effects of temporally restricted feeding on hepatic gene expression of Cry1, Cry2 double KO mice
Restricted feeding impacts the hepatic circadian clock of WT mice. Cry1, Cry2 double KO mice lack a circadian clock and are thus expected to show rhythmical gene expression in the liver. Imposing a temporally restricted feeding schedule on these mice shows how the hepatic circadian clock and rhythm...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-13062 | biostudies-arrayexpress
TranscriptomicsHigh temporal resolution profiling of U2OS fibroblasts
High-temporal resolution profiling was performed on U2OS fibroblasts to detect rhythmic transcripts Keywords: time course Samples were collected every hour for 48 hours from dexamethasone-synchronized U2OS cells. Cells synchronized with dexamethasone for 24 hours, and harvested from the 24th to 71...
ORGANISM(S): Homo sapiens 
2008-12-14 | E-GEOD-13949 | biostudies-arrayexpress
UnknownTime of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression.
Not available
S-EPMC2795502 | biostudies-literature
UnknownReciprocity between phase shifts and amplitude changes in the mammalian circadian clock.
Not available
S-EPMC2154435 | biostudies-literature
UnknownHarmonics of circadian gene transcription in mammals.
Not available
S-EPMC2654964 | biostudies-literature
TranscriptomicsFeeding schedule and the circadian clock shape rhythms in hepatic gene expression
This SuperSeries is composed of the following subset Series: GSE13060: The effects of temporally restricted feeding on hepatic gene expression GSE13062: The effects of temporally restricted feeding on hepatic gene expression of Cry1, Cry2 double KO mice GSE13063: Effects of extensive fasting and sub...
ORGANISM(S): Mus musculus 
2009-11-12 | E-GEOD-13093 | biostudies-arrayexpress
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
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