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Upon fertilisation, the egg must have the resources to facilitate successful fertilisation and regulate zygotic growth prior to the activation of the embryonic genome. A key biomarker of egg activation is the synchronised release of of cortical alveoli (CA) from the egg’s cortex into the perivitelli...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2026-04-27 | PXD073748 | Pride
p130Cas is a polyvalent adapter protein essential for cardiovascular development, and with a key role in cell movement. In order to identify the pathways by which p130Cas exerts its biological functions in endothelial cells we mapped the p130Cas interactome and its dynamic changes in response to VEG...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080860 | MassIVE
Inadequate extracellular conditions can adversely affect the environment of the ER and impinge on the maturation of nascent proteins. The resultant accumulation of unfolded proteins activates a signal transduction pathway, known as the unfolded protein response, which serves primarily to protect th...
ORGANISM(S): Homo sapiens 
Metastatic renal cell carcinoma (mRCC) patients treated with anti-vascular endothelial growth factor (VEGF) therapies demonstrate promising outcomes but not all patients benefit. Factors that predict response remain to be elucidated. Nephrectomy material from 37 patients with mRCC receiving bevacizu...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE33737: Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig [AP] GSE33738: Fetal programming of muscle transcriptome in response to gestational dietary protein levels in the pig [HP] GSE...
ORGANISM(S): Sus scrofa 
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis. Wild type.
ORGANISM(S): Bartonella Henselae Str. Houston-1 
The Bartonella autotransporter BafA mimics host VEGF to drive angiogenesis
ORGANISM(S): Bartonella Henselae Str. Houston-1 
Aim of this experiment was to characterize whether SPP1 released from the hippocampal perivascular space could imprint microglia transcriptional states. We performed scRNA-seq analysis on sorted CD140a+ perivascular fibroblast (PVF), CD45highCD11intCD206+ perivascular macrophage (PVM) and CD45intCD1...
ORGANISM(S): Mus musculus 
German landrace gilts were fed a low protein diet (LP, 6% CP) throughout their whole pregnancy. Subsequently muscle transcriptome profiles of the offspring were analysed at prenatal (94 dpc) and postnatal stages (1, 28, 188 dpn) per stage offspring of 3 gilts were collected for expression profiling
ORGANISM(S): Sus scrofa 
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