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UnknownTonghua Liyan granules in the treatment of Laryngopharyngeal reflux disease with stagnation of phlegm and qi syndrome: a randomized, double-blind, placebo-controlled study.
Not available
S-EPMC10921225 | biostudies-literature
ProteomicsIdentification of ASC-interacting proteins
To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-29 | PXD052497 | Pride
Asc Francisella novicida Inflammasome Bmdm Mouse 
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025076 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
ProteomicsNovel insights into redox-based mechanisms for auranofin- induced rapid cancer cell death
One of the significant features of cancer cells is a persistent pro-oxidative status. Therefore, compared to their normal counterparts, the malignant cells are generally more dependent on antioxidants for cell survival and more vulnerable to further oxidative insults via pharmacolog-ical interventio...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036558 | Pride
Auranofin  oxidative stress  redox regulation  redoxome  cancer 
ProteomicsVitamin C-induced breast cancer cell death is associated with remodeling the redox state of cysteine-containing proteins involved in translation and cell cycle progression
Recent studies show vitamin C (VitC) pro-oxidant properties at high pharmacological concentrations which favor repurposing VitC as an anti-cancer therapeutic agent. However, redox-based anticancer properties of different forms of VitC are yet partially understood. We examined the difference between ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-16 | PXD013833 | Pride
Breast cancer Ascorbic acid Vitamin c Dehydroascorbic acid Oxidative stress Redoxome 
UnknownZe-qi Decoction Inhibits Neutrophil Extracellular Trap Formation to Suppress the Progression and Metastasis of Non-Small Cell Lung Cancer
Not available
S-EPMC12909755 | biostudies-literature
UnknownThe Role of Probiotics in Managing Glucose Homeostasis in Adults with Prediabetes: A Systematic Review and Meta-Analysis.
Not available
S-EPMC10963111 | biostudies-literature
Proteomicsiotin-streptavidin affinity purification mass spectrometry of proteins in human 293T cell using bioinylated Orf9b
COVID-19, caused by the new RNA virus strain SARS-CoV-2, is a serious acute respiratory disease. One of the prominent feature of SARS-COV-2 in terms of immune responses is that it triggers very low level responses of IFN-I in cells or COVID-19 patients. Previously SARS-CoV Orf9b were reported to be ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019803 | Pride
Ap-ms Human 293t cell Silac Sars-cov-2 orf9b 
UnknownEndothelial c-Myc knockout enhances diet-induced liver inflammation and fibrosis.
Not available
S-EPMC11367571 | biostudies-literature
UnknownSub-high Temperature and High Light Intensity Induced Irreversible Inhibition on Photosynthesis System of Tomato Plant (Solanum lycopersicum L.).
Not available
S-EPMC5352666 | biostudies-literature
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