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MetabolomicsMulti-omics reveals that alkaline mineral water improves the respiratory health and growth performance of transported calves

BACKGROUND: Long-distance transportation, a frequent practice in the cattle industry, stresses calves and results in morbidity, mortality and growth suppression, leading to welfare concerns and economic losses. Alkaline mineral water (AMW) is an electrolyte additive containing mu...

2024-06-04 | MTBLS8204 | MetaboLights
MetabolomicsTargeted rewiring of the rhizosphere metabolite-microbe axis restores phosphorus acquisition in inefficient citrus rootstocks
This study aimed to screen citrus rootstocks with contrasting phosphorus (P) efficiency. Seedlings were grown in P-deficient red soil-vermiculite substrate under greenhouse conditions. After 5 months cultivation, plant biomass, leaf P concentration, root architecture, rhizosphere available P and pho...
2026-10-22 | MTBLS15885 | MetaboLights
ProteomicsQuantitative Proteomics Reveals the role of Lysine 2-hydroxyisobutyrylation Pathway mediated by Tip60
Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionary conserved and widespread protein posttranslational modification (PTM) that has diverse cellular functions. Recently, it has been demonstrated that Khib can be regulated by p300 and Tip60. Although the specific Khib substrates mediated by p300...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD029297 | Pride
Lysine 2-hydroxyisobutyrylation Tip60 Posttranslational modification Substrate Quantitative proteomics 
UnknownComplex Age- and Cancer-Related Changes in Human Blood Transcriptome-Implications for Pan-Cancer Diagnostics.
Not available
S-EPMC8554330 | biostudies-literature
ProteomicsQuantitative proteomics revealed the mechanism of Yiqi Huoxue recipe used to treat cerebral infarction with Qi deficiency and blood stasis
Huoxue Yiqi (HXYQ) recipe is widely used to treat cerebral infarction with Qi deficiency and blood stasis syndrome (CI-QDBS), but its pharmacological mechanism is still not clear. In this study, the serum samples of patients with Qi deficiency and blood stasis syndrome in the convalescent stage of c...
ORGANISM(S): Homo Sapiens 
2022-12-12 | PXD029388 |
MetabolomicsPithecellobium clypearia ameliorates ulcerative colitis through regulation of purine metabolism and gut microbiota

Background: Pithecellobium clypearia (PC) is a traditional Chinese medicine with anti-inflammatory effects. However, the therapeutic efficacy and underlying mechanisms of PC in ulcerative colitis (UC) remain unclear.

Objective: This study applied an integrated microbiome-meta...

2026-06-26 | MTBLS14856 | MetaboLights
TranscriptomicsGenomic diversity of Escherichia isolates from diverse habitats
Comparative genomic hybridization between Escherichia coli strains to determine core and pan genome content of clinical and environmental isolates Two color experiment, Escherichia coli Sakai (reference), clinical and environmental Escherichia coli strains (testers): At least two replicates includin...
ORGANISM(S): Escherichia sp. TW14265 
2012-08-30 | E-GEOD-39667 | biostudies-arrayexpress
UnknownDNA damage response-related immune activation signature predicts the response to immune checkpoint inhibitors: from gastrointestinal cancer analysis to pan-cancer validation.
Not available
S-EPMC10976329 | biostudies-literature
UnknownPan-cancer analysis implicates novel insights of lactate metabolism into immunotherapy response prediction and survival prognostication.
Not available
S-EPMC11044366 | biostudies-literature
MetabolomicsNeuropeptide SP protects against colitis and linked anxiety-like behavior via gut microbiota and metabolite inositol: A multi-omics analysis of the gut-brain axis

The gut-brain axis facilitates two-way communication between gut inflammation and psychiatric comorbidities associated with inflammatory bowel disease (IBD). In this study, we examined the neuroprotective effects of the neuropeptide substance P (SP) on colitis. Taking into account the interaction...

2025-11-18 | MTBLS11203 | MetaboLights
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