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UnknownUsing IPA tools to characterize molecular pathways underlying the involvement of IRF7 in antiviral response to HIV.
Not available
S-EPMC9923504 | biostudies-literature
ProteomicsIntegrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer
The project contains raw and result files from a proteomic profiling of a male breast cancer (MBC) case. Label-free quantification-mass spectrometry (LFQ-MS) and bioinformatics analysis were employed to investigate the differentially expressed proteins (DEPs) among distinct tissue samples: the prima...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD012453 | Pride
Proteomics Signaling pathways Label-free mass spectrometry Bioinformatics analysis Male breast cancer 
TranscriptomicsGenome-wide DNA methylation identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity
Previously we have shown that extravillous cytotrophoblast (EVT) outgrowth and migration on a collagen gel explant model were restricted by exposure to decidual natural killer cells (dNK). This study investigates the molecular causes behind this phenomenon. Genome wide DNA methylation of exposed and...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-60885 | biostudies-arrayexpress
UnknownBlood transcriptomics mirror regulatory mechanisms during hibernation-a comparative analysis of the Djungarian hamster with other mammalian species.
Not available
S-EPMC10499953 | biostudies-literature
ProteomicsProteomic Analysis of Retinas from Two Different Type 1 Diabetic Models
Objective To explore the proteomic changes in retina associated with type 1 diabetes mellitus (T1DM) using two different mouse models of diabetic retinopathy (DR). Design Experimental study investigating retinal proteomic changes in Akita and streptozotocin (STZ)-induced diabetic mouse models using ...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-05 | PXD069751 | Pride
Pathways Streptozotocin Spectronaut Proteomic Retinopathy Qiagen ipa Graph prism Mass spectrometry Diabetes Animal models Akita Type-1-diabetes 
TranscriptomicsExpression data from mice on a high fat, high carbohydrate diet treated with exenatide
The present study was constructed to confirm previous findings that mice on a high fat diet (HFD) treated by subcutaneous injection with exenatide (EXE) at 3µg/kg once daily for 6 weeks develop exocrine pancreatic injury (Rouse et al. 2014). The present study included 12 weeks of EXE exposure at mu...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-54774 | biostudies-arrayexpress
TranscriptomicsLong-Term Soy Protein Isolate Intake Reduces Liver Steatosis through Changes in Global Gene Expression in Obese Zucker Rats
To understand how soy protein isolate (SPI) reduced liver steatosis in male obese Zucker rats, we conducted global gene expression (RNAseq) analysis on liver samples of male rats fed either the SPI or a control casein (CAS)-based diet (n=8 per group) for 16 wks. Bioinformatics was conducted using In...
ORGANISM(S): Rattus norvegicus 
2020-11-11 | GSE158553 | GEO
TranscriptomicsTLR4 Signaling Is a Major Mediator of the Female Tract Response to Seminal Fluid in Mice
To examine the effect of seminal fluid on the whole genome expression profile of endometrial tissue following mating, RNA was extracted from endometrial tissue collected 8 h after CBAF1 females were mated with intact Balb/c males and compared to RNA from endometrial tissue of females mated with semi...
ORGANISM(S): Mus musculus 
2015-07-01 | E-GEOD-70401 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression between African American and European American Colorectal Cancer Patients
The incidence and mortality of colorectal cancer (CRC) is higher in African Americans (AAs) than in other ethnic groups in the U. S., but reasons for the disparities are unknown. We performed gene expression profiling and microsatellite instability (MSI) analysis of sporadic CRCs from AAs vs. Europe...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-28000 | biostudies-arrayexpress
TranscriptomicsMesenchymal stromal cells-derived small extracellular vesicles affect T-lymphocytes mRNA expression
In the current research, we further study the immune-modulatory effect of bmMSCs on T cells, by mRNA sequencing of activated T cells co-cultured with bmMSC-sEVs. Methods: activated T lymphocytes were cocultured with and without bmMSC derived sEVs. mRNA profiling was performed using the QIAGEN Illumi...
ORGANISM(S): Homo sapiens 
2025-03-01 | GSE198738 | GEO
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