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SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron homeostasis in COVID-19 patients imply that ferroptosis, an iron-dependent cell death, may occur. Immunostaining and lipidomic an...

2024-07-11 | MTBLS3107 | MetaboLights
Germinal center (GC) response requires increased protein synthesis. We identify the methyltransferase METTL1 as a translational checkpoint during GC responses. Therefore, we immunized mettl1-cko mice and control mice with NP-OVA, and sorted spleen B cells on day 14.
ORGANISM(S): Mus musculus (Mouse) 
2024-11-01 | PXD057426 | Pride
Drosophila Xkr, the Xkr8 homolog, exhibits scramblase activity to mediate PS exposure in apoptosis in a caspase-independent manner, but the mechanism is unclear. So we expressed Xkr-FLAG in Drosophila S2 cells, using shot-gun LC-MS/MS to identify proteins interacting with Xkr.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-09-23 | PXD058895 | Pride
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