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GenomicsDNA methylation analysis of prostate cancer cell lines and tissues using Next Generation Sequencing
Beginning with precursor lesions, aberrant DNA methylation marks the entire spectrum of prostate cancer progression. We mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=2) from fifty nanograms of genomic DNA using Methylplex-Next Generation Sequencing (M-NGS). A...
ORGANISM(S): Homo sapiens 
2011-05-09 | E-GEOD-27618 | biostudies-arrayexpress
UnknownChinese herbal medicine Jia Wei Jing Xie Yin (JWJXY) ameliorates psoriasis via suppressing the Th17 cell response.
Not available
S-EPMC9011239 | biostudies-literature
UnknownSynthesis and thermoelectric properties of InSb alloys by solid reaction.
Not available
S-EPMC6288316 | biostudies-literature
ProteomicsCombined effects of EMP and RF exposure on mouse hippocampus LC-MSMS
Recently, concerns about the combined effects of electromagnetic field (EMF) in daily living and occupational environment are rapidly growing. 4.9 GHz radiofrequency (RF) is commonly used in 5G telecommunication in daily life, EMP is common is occupational environment. Till now, the biological effec...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD038101 | Pride
Lc-msms Mouse Hippocampus 
ProteomicsThe ubiquitin E3 ligase APC/CCdc20 mediates mitotic degradation of OGT
O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is the sole enzyme that catalyzes all O-GlcNAcylation reactions intracellularly. Previous investigations have found that OGT levels oscillate during the cell division process. Specifically, OGT abundance is downregulated during mitosis, but...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050552 | Pride
Uterine carcinoma Ubiquitination Cell cycle Ogt Apc/ccdc20 
TranscriptomicsMicroarray analysis of the miRNA levels in plasma from healthy donors
To further understanding of mature microRNA in plasma from healthy people, we have employed microRNA microarray as a discovery platform with the potential to identify the plasma microRNA levels of healthy people. Human peripheral blood was drawn from 4 healthy donors, and plasma was obtained by two-...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-23390 | biostudies-arrayexpress
UnknownDeciphering the crosstalk of immune dysregulation between COVID-19 and idiopathic inflammatory myopathy
Not available
S-EPMC10449257 | biostudies-literature
GenomicsDNA Methylation Analysis of Prostate Cancer Cell Lines and Tissues Using Next Generation Sequencing

Aberrant DNA methylation changes are known to occur during prostate cancer progression beginning with precursor lesions. Utilizing fifty nanograms of genomic DNA in Methylplex-Next Generation Sequencing (M-NGS) we mapped the global DNA methylation patterns in prostate tissues (n=17) and cells (n=...

phs000597.v1.p1 | EGA
ProteomicsO-GlcNAcylation stabilizes ULK1 by inhibiting chaperone-mediated autophagy upon HPV infection
Human papillomaviruses (HPVs) are conducive to a fraction of head and neck squamous cell carcinoma (HNSCC). Previously we demonstrated that HPV16 oncogene E6 or E6/E7 transduction increases the abundance of O-linked GlcNAcylation (O-GlcNAc) transferase (OGT). Herein we focus on the effects of O-GlcN...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031095 | Pride
O-glcnac  ulk1  hpv  hnscc  macroautophagy  chaperone-mediated autophagy 
MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
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