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UnknownSeparating Functions of the Phage-Encoded Quorum-Sensing-Activated Antirepressor Qtip.
Not available
S-EPMC7148176 | biostudies-literature
ProteomicsThe Human Telomeric Proteome During Telomere Replication
Telomere shortening can cause detrimental diseases and contribute to aging. It occurs due to the end replication problem in cells lacking telomerase. In addition, recent evidence revealed that telomere shortening can be attributed to difficulties of the semi-conservative DNA replication machinery to...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD018712 | Pride
Pot1 Telomeres Ipond Telomere fragility Histone h1 Qtip Dna replication 
UnknownMechanism underlying the DNA-binding preferences of the Vibrio cholerae and vibriophage VP882 VqmA quorum-sensing receptors.
Not available
S-EPMC8284805 | biostudies-literature
UnknownA tandem simulation framework for predicting mapping quality.
Not available
S-EPMC5557537 | biostudies-literature
UnknownThe Effects of Moxifloxacin and Gemifloxacin on the ECG Morphology in Healthy Volunteers: A Phase 1 Randomized Clinical Trial.
Not available
S-EPMC10092949 | biostudies-literature
UnknownNatural Silencing of Quorum-Sensing Activity Protects Vibrio parahaemolyticus from Lysis by an Autoinducer-Detecting Phage.
Not available
S-EPMC10274711 | biostudies-literature
UnknownNatural silencing of quorum-sensing activity protects Vibrio parahaemolyticus from lysis by an autoinducer-detecting phage.
Not available
S-EPMC10426928 | biostudies-literature
UnknownThe human telomeric proteome during telomere replication.
Not available
S-EPMC8643687 | biostudies-literature
ProteomicsTransformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1
Telomeres play crucial roles during tumorigenesis inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alters telomeric chromatin composition an...
ORGANISM(S): Homo sapiens (Human) 
2018-07-13 | PXD010088 | Pride
Quantitative proteomics Telomeres Samhd1 Transformation Replication stress 
ProteomicsPeroxiredoxin 1 protects telomeres from oxidative damage preserving chromosome ends for extension by telomerase
With the increase of atmospheric oxygen 2.3 billion years ago, mechanisms evolved to mitigate the toxic effects of oxygen radicals. Telomeres appear particularly susceptible to oxidative damage, which leads to cellular and organismal aging, cancer, cardiac failure and other diseases. Specific mechan...
ORGANISM(S): Homo sapiens (Human) 
2016-12-07 | PXD002626 | Pride
Peroxiredoxin 1  telomeres  oxidative damage  telomerase 
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