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Glucocorticoid Receptor Quaternary Structure Drives Chromatin Occupancy and Transcriptional Outcome
Elucidation of quaternary amine degradation pathway in the methanogen Methanolobus vulcani B1d
ORGANISM(S): Methanolobus Vulcani (ncbitaxon:38026) 
2019-06-26 | MSV000084013 | MassIVE
Identifying tertiary structures and protein binding sites on RNA molecules remains a key challenge in RNA biology. We report a new chemical probing strategy termed multi-site DMS-MaP (msDMS-MaP) that exploits base tautomerization during mutational profiling reverse-transcription to measure typically...
ORGANISM(S): Homo sapiens 
2026-03-21 | GSE285334 | GEO
Identifying tertiary structures and protein binding sites on RNA molecules remains a key challenge in RNA biology. We report a new chemical probing strategy termed multi-site DMS-MaP (msDMS-MaP) that exploits base tautomerization during mutational profiling reverse-transcription to measure typically...
ORGANISM(S): Escherichia coli Tetrahymena Homo sapiens 
2026-03-21 | GSE285333 | GEO
Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing II
Simultaneous mapping of RNA secondary, tertiary, and quaternary structure in living cells by multi-site DMS probing I
Purpose: To investigate the quaternary structures of Rhodopsin-family GPCRs. Method: Analyzed 60 receptors from HEK 293T cells. Results: 1) Most of these receptors are monomers. 2) The phylogenetic distribution of dimers suggests that monomers have an evolutionary advantage due to constraints impose...
ORGANISM(S): Homo sapiens 
2017-08-10 | GSE102461 | GEO
Ubiquitin-dependent proteolysis regulates diverse cellular functions with high substrate specificity. The precision of this regulatory mechanism hinges on the ability of ubiquitin E3 ligases to decode the targets’ degradation signals, i.e. degrons, which canonically present as short linear motifs. H...
ORGANISM(S): Homo sapiens (Human) 
2025-12-29 | PXD053923 | Pride
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