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MetabolomicsPhosphatidylcholine in wheat anthers is a susceptibility factor for Fusarium head blight
Fusarium head blight is a devastating wheat disease that initiates at flowering, with anthers as the preferred infection site. However, the anther-derived molecules driving this susceptibility remain elusive. Here, we identify anther-enriched phosphatidylcholine, particularly PC(18:2/18:2) and PC(16...
2026-06-23 | MTBLS14814 | MetaboLights
TranscriptomicsTRNP1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate
Evolution of the mammalian brain encompassed a remarkable increase in size of cerebral cortex, including tangential and radial expansion, but the mechanisms underlying these key parameters are still largely unknown. Here, we identified the novel DNA associated protein TRNP1 as a regulator of cerebra...
ORGANISM(S): Mus musculus 
2013-04-26 | E-GEOD-40582 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse functionally distinct radial glial subsets
Since the discovery of radial glia as the source of neurons, their heterogeneity in regard to neurogenesis has been described by clonal and time-lapse analysis in vitro. However, the molecular determinants specifying neurogenic radial glia differently from radial glia that mostly self-renew remain i...
ORGANISM(S): Mus musculus 
2008-06-18 | E-GEOD-8034 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of 8 months and 24 months old rat radial and sciatic nerves
The objective of this study was to determine which pathways are significantly regulated with age in sciatic and radial nerves, individually or considering the interaction term. We find a strong signature of the cholesterol biosynthesis pathway being downregulated with age in both nerves, however, th...
ORGANISM(S): Rattus norvegicus 
2016-05-12 | E-GEOD-77022 | biostudies-arrayexpress
TranscriptomicsRadial Migration Assay and Analysis
When either Panc-1 or MiaPaCa-2 were plated as a discrete clump of cells in the middle of a plate, two morphologically distinct populations could be created. The cells on the periphery of the cell cluster migrated away from the region of high cell density and took on a classical mesenchymal phenotyp...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21566 | biostudies-arrayexpress
MetabolomicsA metabolite roadmap of the wood-forming tissue in Populus tremula (UPLC-MS assay; Wood fibre and ray cell tissue)

Wood, or secondary xylem, is the product of xylogenesis, a developmental process that begins with the proliferation of cambial derivatives and ends with mature xylem fibers and vessels with lignified secondary cell walls. Fully mature xylem has undergone a series of cellular processes, including ...

2020-09-01 | MTBLS1831 | MetaboLights
MetabolomicsMetabolite profiling of tubers of an early- and a late-maturing potato line and their grafts

INTRODUCTION: Earliness of tuberisation and the quality of potato tubers are important traits in potato breeding. The qualitative traits rely on the metabolite profile of tubers, which are storage organs and net importers of assimilates. Thus, the quality of tubers largely depend...

2023-09-12 | MTBLS4445 | MetaboLights
GenomicsA radial map of the budding yeast genome reveals novel organizational principles
A radial map of the budding yeast genome reveals novel organizational principles
PRJEB112370 | ENA
ProteomicsThe structure and symmetry of the Radial Spoke protein complex in Chlamydomonas flagella
Chemical cross-linking coupled to mass spectrometry was used to study the organization of the Radial Spoke protein complex from Chlamydomonas. Experiments were performed by on-bead cross-linking of the immobilized complex with the amine-reactive cross-linking reagent disuccinimidyl suberate (DSS).
ORGANISM(S): Chlamydomonas reinhardtii 
2020-08-07 | PXD015658 | Pride
Chemical cross-linking  dss  structural proteomics  radial spoke complex 
TranscriptomicsThe nuclear actin-related protein Arp6 contributes to the radial positioning of chromosome territories.
The chromatin of individual chromosomes is organized into chromosome territories (CTs) in the interphase nucleus. The spatial arrangement of CTs is non-random and evolutionarily conserved. The gene-dense and gene-poor CTs are positioned in the nuclear center and periphery, respectively. As candidate...
ORGANISM(S): Gallus gallus 
2015-11-04 | E-GEOD-14220 | biostudies-arrayexpress
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