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TranscriptomicsExpression data from human adrenocortical H295R cells expressing a doxycyclin-inducible shRNA targeting CTNNB1
We used the H295R cell line, human adrenocortical cells, harboring a heterozygous CTNNB1 (beta-catenin) gene mutation affecting the GSK3 beta-phosphorylation site (S45P) and leading to constitutive transcriptional activity of beta-catenin-LEF/TCF. Whole-transcript gene expression was analyzed in thr...
ORGANISM(S): Homo sapiens 
2015-08-03 | E-MTAB-3330 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of human adrenocortical tumors (ACTs)
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Transcriptome analysis led to the unsupervised classification of carcinomas in two groups, associated with different outcomes {de Reynies, 2009 ; Giordano, 2009}. Subsequent...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-MTAB-815 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP6 array data for ACTH-Independent Macronodular Adrenal Hyperplasia (AIMAH) samples
AIMAH is an ACTH-independent bilateral enlargement of the adrenal cortex occuring during adulthood. The enlargment is related to the growth of multiple benign nodules. This condition is associated with various degrees of cortisol hypersecretion. The occurence of several nodules in both adrenals, and...
ORGANISM(S): Homo sapiens 
2013-11-28 | E-GEOD-42171 | biostudies-arrayexpress
UnknownComparison of the effects of PRKAR1A and PRKAR2B depletion on signaling pathways, cell growth, and cell cycle control of adrenocortical cells.
Not available
S-EPMC4727442 | biostudies-literature
UnknownCircular and linear: a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells.
Not available
S-EPMC9058605 | biostudies-literature
UnknownNuclear Magnetic Resonance Reveals Molecular Species in Carbon Nanodot Samples Disclosing Flaws.
Not available
S-EPMC9304307 | biostudies-literature
UnknownAn Artificial Molecular Transporter.
Not available
S-EPMC4906471 | biostudies-literature
UnknownRemote electrochemical modulation of pKa in a rotaxane by co-conformational allostery.
Not available
S-EPMC6156658 | biostudies-literature
UnknownARMC5 mutations in macronodular adrenal hyperplasia with Cushing's syndrome.
Not available
S-EPMC4727443 | biostudies-literature
UnknownValue of Molecular Classification for Prognostic Assessment of Adrenocortical Carcinoma.
Not available
S-EPMC6624825 | biostudies-literature
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