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MetabolomicsMetabolic profilings of rat INS-1 β-cells under changing levels of essential amino acids

Application of mass spectrometry enables the detection of metabolic differences between organisms with different nutritional settings. Divergence in the metabolic fingerprints of rat pancreatic INS-1 β-cells were systematically captured with regard to 10 individual essential amino acid (EAA) avai...

2022-05-24 | MTBLS3963 | MetaboLights
TranscriptomicsA conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [sRNA-seq]
Co-transcriptional RNA processing and surveillance factors mediate heterochromatin formation in fission yeast. In addition to RNAi, RNA elimination machinery including MTREC (Mtl1-Red1 core) and the exosome are involved in facultative heterochromatin assembly, however, the exact mechanisms remain un...
ORGANISM(S): Schizosaccharomyces pombe 
2016-01-05 | E-GEOD-74739 | biostudies-arrayexpress
GenomicsCandidatus Electrothrix aestuarii isolate:Rat1
Candidatus Electrothrix aestuarii isolate:Rat1 Genome sequencing and assembly
PRJNA995772 | ENA
TranscriptomicsA conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Schizosaccharomyces pombe 
2016-01-05 | E-GEOD-74741 | biostudies-arrayexpress
TranscriptomicsA conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing [ChIP-chip]
Occupancy profiling of lysine 9 dimethylated histone H3 in fission yeast. Occupancy profiling of Red1, Mtl1, and Mmi1 proteins in fission yeast. Agilent 60mer array was used to analyze DNA recovered by immunoprecipitation of lysine 9 dimethylated histone H3, Red1, Mtl1, and Mmi1 proteins from async...
ORGANISM(S): Schizosaccharomyces pombe 
2016-01-05 | E-GEOD-74740 | biostudies-arrayexpress
UnknownA termination-independent role of Rat1 in cotranscriptional splicing.
Not available
S-EPMC8191773 | biostudies-literature
ProteomicsRio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores
Kinetochores assemble on centromeres (CENs) via histone H3 variant CENP-A and low levels of CEN transcripts. RNA polymerase II (RNAPII) activity is restrained by the CEN histone code, while CEN RNA concentrations are reduced by the nuclear exosome. Using S. cerevisiae, we add kinase Rio1 to this sch...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-02-24 | PXD030623 | Pride
Rat1 Kinetochore Centromere Riok1 Pericentromere Rio1 
UnknownStructural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Not available
S-EPMC11381523 | biostudies-literature
UnknownRat1 promotes premature transcription termination at R-loops.
Not available
S-EPMC11039981 | biostudies-literature
UnknownUnraveling the mechanistic features of RNA polymerase II termination by the 5'-3' exoribonuclease Rat1.
Not available
S-EPMC4357727 | biostudies-literature
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