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GenomicsChIP-seq validation of recombinant antibodies to histone post-translational modifications
Recombinant antibodies to histone post-translational modifications (PTMs), with their essentially infinite renewability, could fundamentally eliminate a major source of low reproducibility in epigenetics research. Here, we report new recombinant antibodies to trimethylated Lys4 and Lys9, respectivel...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-66530 | biostudies-arrayexpress
ProteomicsIdentification of proteins in SDS-PAGE gel by LC-MSMS
Recombinant antibodies were purified from culture supernatants derived from the Dictyostelium discoideum model and loaded into an SDS-PAGE electrophoresis gel. The electrophoretic profile of the anti-alpha tubulin, anti-CISD1, and anti-CD8β antibodies reveals a band at 35 kDa, likely corresponding t...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2025-04-11 | PXD053343 | Pride
Dictyostelium discoideum Recombinant antibodies 
ProteomicsPathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury
Intestinal ischemia-reperfusion (IR) injury is initiated when natural IgM antibodies recognize neo-epitopes that are revealed on ischemic cells. The target molecules and mechanisms whereby these neo-epitopes become accessible to recognition are not well understood. Proposing that isolated intestinal...
ORGANISM(S): Mus musculus 
2010-05-05 | E-GEOD-14862 | biostudies-arrayexpress
Genomicsrecombinant coronavirus
Recombinant OC43 SARS-CoV-2 Spike Replacement Virus: An Improved BSL-2 Proxy Virus for SARS-CoV-2 Neutralization Assays
PRJNA1064152 | ENA
GenomicsChIP-seq validation of recombinant antibodies to histone post-translational modifications
Recombinant antibodies to histone post-translational modifications (PTMs), with their essentially infinite renewability, could fundamentally eliminate a major source of low reproducibility in epigenetics research. Here, we report new recombinant antibodies to trimethylated Lys4 and Lys9, respectivel...
ORGANISM(S): Homo sapiens 
2016-03-02 | GSE66530 | GEO
ProteomicsGluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes
This study aimed to identify proteolytic fragments of gluten proteins recognized by recombinant IgG1 monoclonal antibodies generated from single IgA plasma cells of celiac disease lesions. Peptides bound by monoclonal antibodies in complex gut-enzyme digests of gluten treated with the deamidating en...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080779 | MassIVE
ProteomicsShotgun proteomics analysis of protein purifications from human plasma using antibodies and affimers
Antibodies are widely used to purify protein from complex mixtures like human plasma. Assessing the specificity of anntibodies, or any protein binder, is essential for the development of a protein biomarker assay. In addition to antibodies, novel protein binders like affimers are developed with a hi...
ORGANISM(S): Homo sapiens (Human) 
2020-05-29 | PXD016435 | Pride
Antibody Protein purification Affimer Lc-ms/ms 
ProteomicsGeneration and validation of recombinant antibodies to study tRNA synthetases in health and disease
Aminoacyl tRNA synthetases (aaRSs) have long been viewed as mere housekeeping proteins and have therefore often been overlooked in drug discovery. However, recent findings have revealed that many aaRSs have non-canonical functions and several of them have been linked to autoimmune diseases, cancer a...
ORGANISM(S): Homo sapiens (Human) 
2020-08-13 | PXD020104 | Pride
Recombinant antibodies Antibody validation Aminoacyl trna synthetase Phage display 
TranscriptomicsRecombinant and plasma-derived Factor VIII products induce distinct splenic cytokine microenvironments in hemophilia A
To investigate the gene expression in dendritic cells after treating hemiphilic mice with HBSS, plasma derived or recombinant factor VIII Gene expression in dendritic cells were measured 24 hours post treatment Hemophilic mice with treated with either (HBSS, rFVIII or pdFVIII) 24 hours post treatmen...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-15809 | biostudies-arrayexpress
ProteomicsAntibody - pollen allergen immunoprecipitation
Recombinant antibodies were used for immununoprecipitation with pollen extracts to define their specificity
ORGANISM(S): Phleum pratense Holcus lanatus 
2025-12-12 | PXD056681 | Pride
Allergen Immunoprecipitation Recombinant antibodies Pollen 
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