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ProteomicsConus striatus Venom Duct LC/MS/MS
The venom of cone snails is highly variable both between and within species, as well as spatially along the venom duct. However, defferences of defensive and predatory venoms in "hook-and-line" fish hunting clades and their venom duct origins has not been investigated. In this study a combination of...
ORGANISM(S): Conus striatus 
2022-02-17 | PXD026194 | Pride
Conus striatus Tripletof 5600 Trypsin digested Reduced alkylated 
ProteomicsHydrolysis and oxidation of maleimide alkylated peptides
These data show that maleimide-alkylated peptides (MAPs) are oxidized and hydrolysed under sample preparation conditions common for proteomic studies. Gel electrophoresis, gel staining, and proteolytic digestion buffers were optimised to minimise these modifications. Purified glutathione alkylated w...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Gallus Gallus (ncbitaxon:9031) 
2017-03-23 | MSV000080667 | MassIVE
UnknownSelective Gas-Phase Oxidation and Localization of Alkylated Cysteine Residues in Polypeptide Ions via Ion/Ion Chemistry.
Not available
S-EPMC5069694 | biostudies-literature
ProteomicsMammals produce cyclo-octasulfur to suppress lipid peroxidation and ferroptosis
This dataset contains LC-ESI-Q-TOF tandem mass spectrometry data acquired to examine the protein composition of lipid droplets isolated from differentiated mouse 3T3-L1 adipocytes. Lipid droplet-associated proteins were delipidated, reduced, alkylated, and digested with trypsin before analysis by da...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-26 | PXD080540 | Pride
Sulfide oxidoreductase Perilipin Lc-q-tof-ms/ms Lipid droplet proteome Caveolin-1 Dda Enos 
ProteomicsQuantification of the percentage of oxidized cysteine thiols in GrxS12 under normal and H2O2 treatments.
To evaluate the percentage of oxidized cysteine thiols, the GrxS12 proteins underwent either with or without H2O2 treatment were alkylated by iodoacetamide (IAM), reduced with DTT, and subsequently the newly generated free Cys were alkylated with N-ethylmaleimide (NEM). The spectrometric analysis of...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-01-16 | PXD059065 | Pride
Grxs12 H2o2 Oxidized cysteine thiols Quantification 
MetabolomicsNext-generation biomonitoring of the early-life chemical exposome in neonatal and infant development

Exposure to synthetic and natural chemicals is a major environmental risk factor in the etiology of many chronic diseases. Investigating complex co-exposures is necessary for a holistic assessment in exposome-wide association studies. In this work, a sensitive liquid chromatography-tandem mass sp...

2023-10-26 | MTBLS2442 | MetaboLights
ProteomicsComparative salivary proteomics analysis of children with and without dental caries using the iTRAQ/MRM approach
In this study, unstimulated saliva samples were collected from 30 children (age 10-12 years) with no dental caries (NDC, n=10), low dental caries (LDC, n=10), and high dental caries (HDC, n=10). Salivary proteins were extracted, reduced, alkylated, trypsin digested and labeled with isobaric tags for...
ORGANISM(S): Homo Sapiens 
2017-12-19 | PXD008488 |
UnknownBiofunctionalization on alkylated silicon substrate surfaces via "click" chemistry.
Not available
S-EPMC3059218 | biostudies-literature
TranscriptomicsLoss of alkyladenine DNA glycosylase alters gene expression in developing mouse brain and leads to reduced anxiety and increased exploratory behavior
Neurodevelopment is a tightly coordinated process, in which genome is exposed to spectra of endogenous agents at different stages of differentiation. Increasing body of evidence suggests that DNA damage is an important feature of developing brain, tightly linked to gene expression programs and neuro...
ORGANISM(S): Mus musculus 
2024-02-01 | GSE243469 | GEO
ProteomicsDefining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium
Identifying all essential genomic components is critical for the assembly of minimal artificial life. In the genome-reduced bacterium Mycoplasma pneumoniae, we found, that small ORFs (smORFs; <100 residues), accounting for 10% of all ORFs, are the most frequently essential genomic components (53%)....
ORGANISM(S): Mycoplasma pneumoniae M29 
2015-03-03 | PXD001611 | Pride
Minimal genome Small proteins Non-coding rnas 
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