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ProteomicsThe platelet releasate in healthy population and pregancy
Upon activation, platelets release a multitude of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). This PR plays an important role in haemostasis, wound healing and the inflammatory response. We and others have used qualitative/quantitative proteomic approaches to ch...
ORGANISM(S): Homo sapiens (Human) 
2018-06-25 | PXD009310 | Pride
Human Platelets Platelet releasate Pregnancy Lc-ms/ms 
ProteomicsProteomics of motor enriched fraction (ATP releasate) from Dictyostelium discoideum
Intracellular transport is regulated by the presence of motor proteins and its adapters on cargoes. Here, we are investigating the role of specific lipid on cargo in recruitment of these motor proteins and adapters. The proteomics were conducted to catalog for the possible adaptors, regulators, and ...
ORGANISM(S): Dictyostelium discoideum (Slime mold) 
2024-05-16 | PXD051777 | Pride
Dictyostelium Supported lipid bilayer Atp releasate Proteomics 
GenomicsMicrovascular Endothelial Cell RNA-Seq: Treatment with Platelet Releasate from COVID-19 & Control Donors
Microvascular Endothelial Cell RNA-Seq: Treatment with Platelet Releasate from COVID-19 & Control Donors
PRJNA736408 | ENA
ProteomicsComparative platelet releasate proteome profiling of acute coronary syndrome versus stable coronary artery disease
Upon activation, platelets release a host of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). The contents of this PR play a significant role in haemostasis, inflammation, and pathologic sequelae. Despite this, proteomic studies investigating the PR in coronary arter...
ORGANISM(S): Homo sapiens (Human) 
2020-06-05 | PXD009356 | Pride
Platelet releasate Proteomics Platelets Acute coronary syndrome Stable coronary artery disease Lc-ms/ms 
ProteomicsThe platelet releasate in healthy population and pregancy
Upon activation, platelets release a multitude of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). This PR plays an important role in haemostasis, wound healing and the inflammatory response. We and others have used qualitative/quantitative proteomic approaches to ch...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-29 | MSV000082866 | MassIVE
ProteomicsQuantification of sulfenic acid modifications in an atherosclerotic model
Physiological stimuli such as thrombin or pathological stimuli such as lysophosphatidic acid (LPA) activate platelets. The activated platelets bind to monocyte through P-selectin-PSGL-1 interactions, but also release the contents of their granules, which were defined as platelet releasate. It is kno...
ORGANISM(S): Homo sapiens (Human) 
2016-10-10 | PXD003365 | Pride
Sulfenic acid Biotin switch assay Atherosclerosis 
ProteomicsQuantification of sulfenic acid modifications in an atherosclerotic model-2
Physiological stimuli such as thrombin or pathological stimuli such as lysophosphatidic acid (LPA) activate platelets. The activated platelets bind to monocyte through P-selectin-PSGL-1 interactions, but also release the contents of their granules, which were defined as platelet releasate. It is kno...
ORGANISM(S): Homo sapiens (Human) 
2016-10-10 | PXD003363 | Pride
Sulfenic acid Biotin switch assay Atherosclerosis 
ProteomicsHigh precision platelet releasate definition by quantitative reversed protein profiling
The platelet releasate defined by quantitative reversed protein profiling. Dimethyl labeled proteins of platelets in resting (light label) and activated state (collagen and thrombin activation, intermediate label) from three healthy volunteers fractionated by SCX, analyzed on a LTQ Obitrap Velos us...
ORGANISM(S): Homo sapiens (Human) 
2014-02-03 | PXD000072 | Pride
Human Lc-msms Releasate Blood Ltq orbitrap velos Isotope labeling Platelets Alpha granules 
UnknownProteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate.
Not available
S-EPMC2846341 | biostudies-literature
UnknownThe Releasate of Avascular Cartilage Demonstrates Inherent Pro-Angiogenic Properties In Vitro and In Vivo.
Not available
S-EPMC8721614 | biostudies-literature
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