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UnknownDietary patterns and physical activity in young South Asians and white Europeans and their potential implications for cardiovascular risk.
Not available
S-EPMC12000287 | biostudies-literature
GenomicsChromatin accessibility maps of chronic lymphocytic leukemia identify subtype-specific epigenome signatures and transcription regulatory networks
Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity, despite relatively few genetic alterations. To provide a basis for studying epigenome deregulation in CLL, we established genome-wide chromatin accessibility maps for 88 CLL samples from 55 patients using the ...
ORGANISM(S): Homo sapiens 
2016-06-26 | E-GEOD-81274 | biostudies-arrayexpress
UnknownVariability of flow-mediated dilation across lower and upper limb conduit arteries.
Not available
S-EPMC11519148 | biostudies-literature
ProteomicsChromatin isolation for mass spectrometry
The histone acetyl-reader BRD4 is an important regulator of chromatin structure and transcription, yet factors modulating its activity have remained elusive. Here we describe two complementary screens for genetic and physical interactors of BRD4, which converge on the folate pathway enzyme MTHFD1. W...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD013090 | Pride
Transcription Brd4 Mthfd1 Folate metabolism Gene regulation 
UnknownAnthocyanins Promote Learning through Modulation of Synaptic Plasticity Related Proteins in an Animal Model of Ageing.
Not available
S-EPMC8388918 | biostudies-literature
UnknownUltra-high-throughput single-cell RNA sequencing and perturbation screening with combinatorial fluidic indexing.
Not available
S-EPMC7612019 | biostudies-literature
UnknownPooled CRISPR screening with single-cell transcriptome readout.
Not available
S-EPMC5334791 | biostudies-literature
UnknownCan 4 weeks of real-world active breaks improve glycaemic management in sedentary adults with type 1 diabetes? The EXTOD-Active randomised control trial protocol.
Not available
S-EPMC11973742 | biostudies-literature
ProteomicsSystematic characterization of BAF mutations explains intra-complex synthetic lethalities
Aberrations in genes coding for subunits of the BAF chromatin remodeling complex are highly abundant in human cancers. Currently, it is not understood how these loss-of-function mutations contribute to cancer development and how they can be targeted therapeutically. The cancer type specific occurren...
ORGANISM(S): Homo sapiens (Human) 
2019-08-01 | PXD013102 | Pride
Atac-seq Interaction proteomics Chromatin remodeling Baf complex Chromatin accessibility Chromatin binding Transcriptomics Synthetic lethality Mammalian swi/snf complex 
UnknownThe Role of AKT3 Copy Number Changes in Brain Abnormalities and Neurodevelopmental Disorders: Four New Cases and Literature Review.
Not available
S-EPMC6395382 | biostudies-literature
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